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Demographic and health characteristics of stroke patients admitted to Ayatollah Rouhani hospitals, 2014-2015.
Source publication
Background
Stroke is the second leading cause of death worldwide and is associated with several risk factors with variable risk factor distribution by population. We report the types and frequency of the associated factors of stroke in north Iran.
Methods
Consecutive patients with stroke were recruited from 2014 to 2015. The two groups of ischemic...
Context in source publication
Citations
... Another study in Iran Indicates that 20% of Hemorrhagic stroke patients have a history of diabetes mellitus and there is a significant relationship between them (P = 0.041) [6]. Out of 36 participants, it was found that 50% of hemorrhagic stroke patients have diabetes mellitus [7]. In a meta-analysis, It was found that 26% of hemorrhagic stroke patients had diabetes [3]. ...
... The reason for this variation may lie in the diet, exercise, and the geographical difference. In the International Journal of Stroke in 2017, it was found that 50% of hemorrhagic stroke patients have diabetes mellitus [7]. In 2018 the Journal of Tropical Medicine in Sub-Saharan Africa; shows that 10.6% of hemorrhagic stroke patients have diabetes mellitus [2]. ...
Introduction: Stroke is the third leading cause of death in the world. Numerous studies show that diabetes mellitus is one of the risk factors for stroke. In general, stroke is divided into two types: hemorrhagic & ischemic, and approximately 15-25% of strokes are the hemorrhagic type. Objective: As it is claimed that diabetes mellitus is an important risk factor for hemorrhagic stroke, this study attempts to explain the association between diabetes and hemorrhagic stroke. Method and Data Collection: According to Epi Info statistic software; 102 participants who were 40≥ years old, and had a hemorrhagic stroke in their brain CT scan or MRI, were selected as cases, and 255 Participants without having a hemorrhagic stroke, including as controls. The proportional distribution of cases and controls in terms of sex and age was considered. Data has been obtained primarily through the design of a questionnaire from admitted patients in the neurosurgery and neurology wards of Aliabad university hospital. Results: Out of 357 participants, 181 (50.7%) participants were female and 176 (49.3%) were male. The study found that 25.5% of the participants in the case group, and 13.3% of the participants in the control group, were exposed to diabetes mellitus. Considering (P-Value = 0.006) and Odds ratio (OR=2.224; 95% CI = 1.253 – 3.945), the association between hemorrhagic Stroke and diabetes mellitus is suggested to be significant. Conclusion: As a result of the study, we can claim that among other risk factors, Diabetes Mellitus can also be considered a possible predisposing factor for Hemorrhagic Stroke and there is a significant association between Hemorrhagic stroke and Diabetes mellitus.
... (13) En el ACV isquémico, en todos los grupos etarios predominaron los varones, siendo similar en el grupo etario de 76 a más años. Se ha reportado que las mujeres eran significativamente mayores que los hombres en el momento del ACV (14) y que, en pacientes mayores de 50 años, el ACV isquémico ocurrió más en mujeres que varones (15) . Por otro lado, en el ACV hemorrágico no se encontró diferencias según sexo; sin embargo, en un estudio la edad media de inicio del ACV hemorrágico fue menor en los hombres que en las mujeres. ...
Objetivo:
Describir el perfil epidemiológico de los pacientes con secuelas de accidente cerebrovascular (ACV) atendidos en un instituto de rehabilitación de Lima-Perú.
Material y métodos:
Estudio observacional, transversal, descriptivo y relacional, de los pacientes con secuelas de ACV atendidos en el periodo 2013 al 2019, en el Instituto Nacional de Rehabilitación “Dra. Adriana Rebaza Flores” AMISTAD PERÚ-JAPÓN. Se recolectaron datos de variables sociodemográficas, clínicas, enfermedades crónicas, hábitos nocivos y medicamentos.
Resultados:
El 71,5% de pacientes tenían secuelas de ACV de etiología isquémica y el 87,6% secuelas moderadas o severas. La mayor frecuencia de pacientes con secuela de ACV isquémico fue a partir de los 56 años (80,7%); mientras que en el ACV hemorrágico fue a partir de los 46 años (61,8%). El 81,7% presentó hemiplejía, el 58% deficiencia en la comunicación y solo el 2,1% en la audición, el 67,3% hipertensión arterial y el 16,1% refirió algún grado de consumo de tabaco. La mayoría de los pacientes con secuelas leves, moderadas y severas eran casados o convivientes. A mayor severidad, era mayor el porcentaje de mujeres, personas mayores e iletradas.
Conclusiones:
La mayoría de los pacientes con ACV tenían secuelas moderadas o graves, hemiplejía, deficiencia de la comunicación e hipertensión. Los pacientes con ACV isquémico tenían mayor edad que aquellos con ACV hemorrágico. A mayor severidad, había mayor porcentaje de personas mayores, mujeres e iletrados.
... It can be either ischemic (caused by the lack of blood flow) or hemorrhagic (caused by bleeding). Finding effective treatments for stroke is a clinical need as it continues to remain as one of the leading causes of death worldwide [77]. ...
Mesenchymal stem/stromal cells (MSCs) have been carefully examined to have tremendous potential in regenerative medicine. With their immunomodulatory and regenerative properties, MSCs have numerous applications within the clinical sector. MSCs have the properties of multilineage differentiation, paracrine signaling, and can be isolated from various tissues, which makes them a key candidate for applications in numerous organ systems. To accentuate the importance of MSC therapy for a range of clinical indications, this review highlights MSC-specific studies on the musculoskeletal, nervous, cardiovascular, and immune systems where most trials are reported. Furthermore, an updated list of the different types of MSCs used in clinical trials, as well as the key characteristics of each type of MSCs are included. Many of the studies mentioned revolve around the properties of MSC, such as exosome usage and MSC co-cultures with other cell types. It is worth noting that MSC clinical usage is not limited to these four systems, and MSCs continue to be tested to repair, regenerate, or modulate other diseased or injured organ systems. This review provides an updated compilation of MSCs in clinical trials that paves the way for improvement in the field of MSC therapy.
... Another study in Iran Indicate that 20% of Hemorrhagic stroke patients have a history of diabetes mellitus and there is significant relationship between them ( P = 0.041) [6]. Out of 36 participants, it was found that 50% of hemorrhagic stroke patients have diabetes mellitus [7]. In a meta-analysis, It was found that 26% of hemorrhagic stroke patients had diabetes [3]. ...
... The reason for this variation may lie in the diet, exercise and the geographical difference. In the International Journal of Stroke in 2017, it was found that 50% of hemorrhagic stroke patients have diabetes mellitus [7]. In 2018 the Journal of Tropical Medicine in Sub-Saharan Africa; shows that 10.6% of hemorrhagic stroke patients have diabetes mellitus [2]. ...
Introduction: Stroke is the third leading cause of death in the world. Numerous studies show that diabetes mellitus is one of the risk factors for stroke. In general, stroke is divided into two types: hemorrhagic & ischemic, and approximately 15-25% of strokes are the hemorrhagic type. Objective: As it is claimed that diabetes mellitus is an important risk factor of hemorrhagic stroke, in this study, an attempt is made to explain the association between diabetes and hemorrhagic stroke. Method and Data Collection: According to Epi Info statistic software; 102 participants who were 40_ years old, and had a hemorrhagic stroke in their brain CT scan or MRI, were selected as cases, and 255 Participants without having a hemorrhagic stroke, included as controls. The proportional distribution of cases and controls in terms of sex and age was considered. Data has been obtained primarily through the design of a questionnaire from admitted patients in the neurosurgery and neurology wards of Aliabad university hospital. Results: Out of 357 participants, 181 (50.7%) participants were female and 176 (49.3%) were male. The study found that 25.5% of the participants in the case group, and 13.3% of the participants in the control group, were exposed to diabetes mellitus. Considering (P-Value = 0.006) and Odds ratio (OR=2.224; 95% CI = 1.253 - 3.945), the association between hemorrhagic Stroke and diabetes mellitus is suggested to be significant. Conclusion: As a result of the study, we can claim that among other risk factors, Diabetes Mellitus can also be considered a possible predisposing factor for Hemorrhagic Stroke and there is a significant association between Hemorrhagic stroke and Diabetes mellitus.
... All these tools consider the patient's clinical condition and signs and symptoms. On the other hand, many studies highlight the importance of comorbidities as risk factors for suffering a stroke (Ahangar et al., 2018;Grysiewicz et al., 2008;Habibi-koolaee et al., 2018;O'Donnell et al., 2016;Xing et al., 2020) and not on how it influences the evolution of the disease. Furthermore, the influence of drugs on the survival time or risk of death of post-stroke patients is unknown. ...
Stroke is a neurological disease. High mortality and sequelae that cause physical or psychological disability demand greater efforts for adequate therapeutic management. The present study aimed to identify signs, symptoms, comorbidities, and therapeutic agents associated with decreased survival time and increased death risk in hospitalized stroke patients. Medical records of stroke patients hospitalized in 2016 at a Peruvian hospital were included. Post-stroke survival time was determined using the Kaplan-Meier method. A comparison of the mean survival time of ischemic and hemorrhagic stroke patients was carried out with the Mantel-Cox test. In addition, the death risk or hazard ratio (HR) was determined using Cox proportional hazards model. The mean survival time was 34.37 (95% CI, 31.89-36.85) and 16.96 (95% CI, 12.35-21.56) days in post-ischemic and hemorrhagic stroke patients, respectively. Dyspnea, peripheral edema, sensory disorder, diffuse cerebral edema and previous stroke are associated with a decrease in survival time. In addition, multivariate analysis revealed that chronic kidney failure (HR=11.98; 95% CI, 2.33-61.68; p=0,003), dyslipidemia (HR=5.19; 95% CI, 1.65-16.32; p=0.005), previous stroke (HR=1.51; 95% CI, 0.41-5.63; p=0.043), and use of antihemorrhagic (HR=1.12; 95% CI, 0.79-1.59; p=0.002) or antiepileptic drugs (HR=1.08; 95% CI, 0.70-1.68; p=0.016) could be considered as death predictors. Clinical and pharmacotherapeutic factors associated with a decrease in mean survival time and increased death risk in hospitalized stroke patients were identified. These factors should be an alarm sign to provide special and timely medical care that reduces the risk of death in patients.
... KK Anderson et al found that presence of diabetes favoured ischemic 7 stroke more than haemorrhagic. similarily, AA Ahangar et al found that diabetes was more prevalent in ischemic than haemorrhagic 8 stroke. ...
Objective The study was done to compare the risk factors, lipid prole, and ECG changes in patients of ischemic and haemorrhagic stroke. Methodology All patients clinically and radiologically diagnosed to be ischemic or haemorrhagic stroke, detailed history, clinical examination, ECG, CT scan brain and routine blood investigation was done on arrival.MRI brain was done when required. Repeat CT scan brain and clinical evaluationwas done after 24 hours to look for complications or improvements, as well as ECG was repeated to look for development of any further changes and comparison was made. Results Out of 80 patients, 34(42.5%) suffered from Haemorrhagic stroke and 46(57.5%) suffered from ischemic stroke. Out of 34 patients who suffered from haemorrhagic stroke 25 had history of hypertension, 22 had history of diabetes, 20 had history of smoking, 12 had history of stroke, 22 had history of alcohol intake, 8 was found to have obesity, and 12 had sedentary lifestyle. Out of 46 ischemic stroke patients, 44 had history of hypertension, 34 had history of diabetes, 24 had history of smoking, 18 had history of stroke, 22 had history of alcohol intake, 9 were obese, and 23 had sedentary lifestyle. Lipid prole was found to be elevated in both type of stroke, however, total cholesterol and LDL were more in ischemic comparatively, while HDL and triglyceride was higher in haemorrhagic. ECG changes were seen in 52.5% of the patients and were more common in haemorrhagic stroke. Conclusion It was seen that the risk factors such as older age, hypertension, diabetes, dyslipidemia, sedentary lifestyles favoured ischemic stroke and smoking, alcohol, obesity favoured haemorrhagic stroke. Higher cholesterol and LDLlevels favoured ischemic more than haemorrhagic stroke. ECG changes were more common in haemorrhagic stroke
... Stroke is the second leading cause of death worldwide. [1][2][3] Complications of stroke are a major cause of death in the acute and subacute phases and can persist in survivors many years after the events. [4,5] Brain injuries, particularly due to stroke, have been well established as a cause of gastrointestinal disorders and manifested as alterations in bowel function such as constipation of varying severity. ...
Background:
Structural planning is essential for the management of constipation in stroke patients. The current study aims to determine the impact of a care plan on the frequency of new-onset constipation following stroke. Materials and Methods.
Materials and methods:
This clinical trial was conducted on 132 stroke patients (two groups of 66) in three phases (pre-intervention, during discharge, 1 month after discharge). Clients were randomly assigned to blocks based on gender, type of stroke, and age. The care plan according to the nursing process was conducted. Data collection tools included a demographic-clinical information questionnaire, Rome IV criteria (diagnosis of constipation), and Bristol scale (consistency of stool). Data were analyzed using the Chi-square, McNemar, Wilcoxon, Analysis of Variance (ANOVA), and a general estimated model.
Results:
The prevalence of new-onset constipation following stroke in the control group decreased from 66 (100%) at admission to 39 (67.20%) at discharge and in the intervention group from 66 cases (100%) to 18 cases (34%) (p = 0.001), but it was not significant at follow-up (p = 0.16). The trend of frequency of constipation from admission to follow-up was generally significant in the intervention group (p = 0.03) vs the control group (p = 0.21). The difference in the mean number of cases of constipation was statistically significant (2.89) 2.10) control group vs 1.58 (1.65) intervention group, p < 0.001).
Conclusions:
A significant impact of the care plan was observed from admission to discharge, but further follow-up was required with more client-side collaboration. Therefore, the present care plan is recommended in the hospital and home care.
... Stroke and its complications, such as constipation, can lead to mortality and disability [20,21]. For the management of constipation, scientific methods, such as formal consensus development (including RAM), provide a timely and efficient solution when evidence is insufficient [22]. ...
Introduction: The impacts of new-onset constipation outcomes in stroke clients have remained unclear. It seems helpful to update the structure planning with nursing-led intervention.
Objective: The current study aimed to present a protocol and methods of Caspian Nursing Process Projects in new-onset constipation by nursing-led intervention considering the experts’ point of view.
Materials and Methods: The current multi-stage evolutionary study describes the protocol and methods of Caspian Nursing Process Projects, which were conducted on stroke constipation, such as new-onset constipation. The study was conducted in several phases, including searching for scientific sources, formal-content validity, RAND and Delphi methods, and changes made at the Delphi stage and the experts’ panel. We selected 21 studies published between January 2004 and December 2019 in the Cochran database, Medline, Science Direct, PubMed, Elsevier, and Scopus. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and AGREE II (The Appraisal of Guidelines for Research & Evaluation) were used to evaluate the articles and guidelines.
Results: After considering the inclusion and exclusion criteria, 14 articles and guidelines were entered. Most of the authorities were 16 men (72.7%), 11 cases had MD degrees (50%), and 4 (18.2%) were neurologists. Regarding the priority, the highest agreement was found on patient and companion education (98%) and the lowest on disability in daily activity (75.6%). In terms of benefits, patient education again achieved the highest agreement with 97.2%, and use of the Bartel index with 73.6% obtained the lowest agreement. Regarding the applicability, registration, and reporting, the water and electrolyte impairment and educational booklet obtained the highest agreement with 93.6%.
Conclusion: All recommendations had reached over 70% agreement in all four areas of the initial draft, and some care should be taken only by stroke nurses or critical care nursing. The study results can be used for developing national guidelines or criteria.
... This is according to a concentrate by Ahangar AA, et al. (2018) who showed that men have a 30% more risk of having a stroke than women. (Ahangar et al., 2018) According to Patricia et al. (2013), most patients with ischemic stroke are male. (Patricia, Kembuan and Tumboimbela, 2015) Studies on the comparison between the number of neutrophils and the clinical outcome of ischemic stroke are still varied. ...
... However, hyperlipidemia, MI, AF, and HF show higher influence in men [71]. While men are more likely to experience stroke than premenopausal women, similar incidences of stroke have been recorded between men and postmenopausal women [69,107]. Sex differences according to the type of stroke have also been reported: brain infarctions and ICHs are more common in men, whereas subarachnoid hemorrhages are more common in women [69]. ...
The impacts of sex differences on the biology of various organ systems and the influences of sex hormones on modulating health and disease have become increasingly relevant in clinical and biomedical research. A growing body of evidence has recently suggested fundamental sex differences in cardiovascular and cognitive function, including anatomy, pathophysiology, incidence and age of disease onset, symptoms affecting disease diagnosis, disease severity, progression, and treatment responses and outcomes. Atrial fibrillation (AF) is currently recognized as the most prevalent sustained arrhythmia and might contribute to the pathogenesis and progression of vascular cognitive impairment (VCI), including a range of cognitive deficits, from mild cognitive impairment to dementia. In this review, we describe sex-based differences and sex hormone functions in the physiology of the brain and vasculature and the pathophysiology of disorders therein, with special emphasis on AF and VCI. Deciphering how sex hormones and their receptor signaling (estrogen and androgen receptors) potentially impact on sex differences could help to reveal disease links between AF and VCI and identify therapeutic targets that may lead to potentially novel therapeutic interventions early in the disease course of AF and VCI.
