Figure - available from: BMC Cancer
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De novo lipogenesis in adipose tissues. TCA: tricarboxylic cycle. ACL: ATP-citrate lyase. ACC: acetyl-coA carboxylase. FAS: fatty acid synthase. SCD1: stearoyl-CoA desaturase-1
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Background
Lung cancer is one of the most lethal tumors with a poor survival rate even in those patients receiving new therapies. Metabolism is considered one of the hallmarks in carcinogenesis and lipid metabolism is emerging as a significant contributor to tumor metabolic reprogramming. We previously described a profile of some lipid metabolism r...
