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Solanum anomalum, a medicinal plant, used in ethnomedicine for their antimalarial, antidiabetic, and antiphlogistic activities was investigated for cytotoxic and genotoxic effects on the root meristem cells of Allium cepa. The extract and fractions was also screened for total flavonoid and phenol content using standard methods. Onion bulbs were exp...
Contexts in source publication
Context 1
... effects of Solanum anomalum leaf extract on levels of the physicochemical parameters (root number and root length) are presented in Table 1. This result shows that all tested concentrations of Solanum anomalum extract caused significant inhibition in the growth of roots in comparison to negative control and positive control. ...Context 2
... root length averages in negative and positive control (methotrexate) groups were 4.16 ± 1.26 and 0.25 ± 0.22 cm respectively. However, average root lengths in 10 mg/mL treatment group was decreased significantly compared to that of the negative control; 0.39 ± 0.19 and 0.44 ± 0.10 cm) for S. anomalum (Table 1). Average root lengths in treatment groups were decreased depending on concentration, significantly (p<0.05) when compared to negative control. ...Context 3
... root morphology was nearly normal during the negative control treatment, but changes in appearance of the roots were observed in the groups treated with 2.5 -10 mg/mL of S. anomalum leaf extract. The roots appearances turned from slight yellow at 5 mg/ml to slight brown at 10 mg/ml of the extract (Table 1). Table 2 shows the effects of Solanum anomalum leaf extracts on cytogenetic parameters of Alium cepa roots. ...