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Compound–Target Network of ZCL. The pink circle represents the 14 active compounds of ZCL; the edges represent the relation of compounds and targets nodes; and the purple hexagon represents the targets of compounds. The node size of gene targets and compounds is proportional to the Degree value

Compound–Target Network of ZCL. The pink circle represents the 14 active compounds of ZCL; the edges represent the relation of compounds and targets nodes; and the purple hexagon represents the targets of compounds. The node size of gene targets and compounds is proportional to the Degree value

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We investigated the mechanisms underlying the effects of Ziziphora clinopodioides Lam. (ZCL) on atherosclerosis (AS) using network pharmacology and in vitro validation.We collected the active components of ZCL and predicted their targets in AS. We constructed the protein-protein interaction, compound-target, and target-compound-pathway networks, an...

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