Table 1 - uploaded by Mohamed Fadhel Najjar
Content may be subject to copyright.
Source publication
The aim of this study is to assess the clinical and biological characteristics of renal stone disease among children living in the coastal region of Tunisia. This retrospective multi-center study included 100 children under the age of 16 years, who presented with urinary stones. The patients' charts were reviewed with regard to age at diagnosis, se...
Context in source publication
Context 1
... composition of stones was homogeneous in 44.0%. Whewellite (calcium oxalate) was found in 77 stones (77.0%), followed by ammonium urate in 49 stones (49.0%) and struvite in nine stones (9.0%) ( Table 1). The composition of the stone section was predominantly whewellite in 69.0% of cases, and predominantly ammonium urate in 47.0% (Table 2); whewellite was the principal compound in only 19% of the cases (Table 3). ...
Similar publications
Kidney stones are a potential risk factor for chronic kidney disease. The impact of different urinary stone components on renal function is unknown. In this study, we retrospectively reviewed 1,918 medical records of patients with urolithiasis. The renal function was evaluated as estimated glomerular filtration rate. All the stones were analyzed by...
This study reports on trends in canine and feline urolithiasis in Canada during the past 10 years. Age, sex, breed of animals and mineral composition from 40 637 canine and 11 353 feline bladder uroliths submitted to the Canadian Veterinary Urolith Centre between 1998 and 2008 were recorded. Struvite and calcium oxalate uroliths comprised > 85% of...
Background:
The combination of infrared spectroscopy and morphological analysis significantly improves the urinary stone analysis. In addition to common urinary stones, it is not unusual to encounter spurious or factitious stones that, if not appropriately identified, can lead to errors in the diagnosis. In this study, we show the importance of In...
Studies that evaluate the effect of age on stone composition are scarce. The aim of this study was to highlight the changes in epidemiological characteristics (stone composition and location) of urolithiasis according to patients' age.
We studied 1,301 urolithiasis patients with age ranging from 6 months to 92 yr (781 males and 520 females). Stone...
To determine frequency of and interval until recurrence after initial ammonium urate, calcium oxalate, and struvite uroliths in cats and whether breed, age, or sex was associated with increased risk for urolith recurrence.
Case-control study.
4,435 cats with recurrent uroliths.
To identify recurrence of uroliths in cats for which uroliths were subm...
Citations
... In cases where multiple studies involved the same or overlapping patient population, we selected the most recent study. The following studies were excluded for this reason [7][8][9][10][11]. ...
... A total of 1,143 studies were screened after the initial database search and deduplication, and only 16 studies met the eligibility criteria. After undergoing full-text screening, five studies [7][8][9][10][11] were excluded as they had the same or overlapping patient population and one study [12] was also excluded as it was carried out only in patients with renal tract malformations. Ten studies were used in this review. ...
Renal stones are solid deposits formed from minerals and salts that develop within the kidneys and urinary tract. While the condition is more common among adults, children and even infants can also be affected. There is an increasing incidence of paediatric renal stones in Africa alongside multiple challenges faced in managing the condition. This scoping review aimed to provide an overview of the management modalities of paediatric renal stones in Africa. This study utilised Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) checklist. A systematic search was conducted in three electronic databases: PubMed, African Journal Online (AJOL), and Google Scholar, with 1,180 articles curated. After extensive examination, 10 articles satisfied the inclusion criteria. The review found that calcium oxalate stones were the most prevalent type, accounting for 34.03% of cases, followed by whewellite stones and ammonium urate stones. The most frequent location for stones was the kidney, and the most common symptom was pain. Abdominopelvic ultrasound was the most frequently utilised investigation. Of the 886 patients managed for renal stones, 75.4% were managed surgically, 2.9% medically, and 21.7% spontaneously resolved without intervention. This review identifies opportunities for improving the management of paediatric renal stones in Africa, including the need for standardised diagnostic and treatment protocols and the development of evidence-based guidelines tailored to the African context. Overall, this scoping review provides valuable insights into the patterns and management of paediatric renal stones in Africa and highlights the need for further research to improve the management of this condition in the region.
... It has been established that kidney stones are more common in men. [6,7] In our study, 55% of the patients were male and 45% were female. It has also been reported that children with kidney stones often have a family history of stones. ...
Objectives:
Urinary tract stones are less common in children than in adults. Determining the etiology is the most important step to achieve successful treatment and prevent future recurrence. The aim of this study was to investigate the clinical characteristics and possible risk factors for urinary stone disease in pediatric patients.
Methods:
The data of 126 patients with urinary stone disease who were treated in a pediatric nephrology clinic between 2000 and 2014 were analyzed retrospectively. A total 126 patients were enrolled in the study: 70 (55%) male and 56 (45%) female patients were included. The complaints, age of diagnosis, family histories, and stone location were examined. Direct urine microscopic examination, complete urinalysis, and urine culture were performed for all of the patients. Calcium, uric acid, oxalate, citrate, magnesium, and cystine levels were measured in urine collected in a 24-hour period. Serum electrolyte, blood urea nitrogen, creatinine, calcium, phosphorus, uric acid, and albumin levels were measured. Urinary ultrasound was performed. Stone analysis was conducted using the X-ray diffraction method. The mean age of the patients was 55 months (range: 1-162 months) at presentation.
Results:
In all, 34% of the patients had a family history of urinary stone disease. The rate of previous urinary tract infection was 26%. It was determined that 34% of the patients had been taking vitamin D and 5% had been taking a high dose. Metabolic risk factors determined were: hypercalciuria in 41%, hypocitraturia in 30%, hyperoxaluria in 14%, hyperuricosuria in 10%, and cystinuria in 5%. Among the group, 81% of the patients had kidney stones, 6.5% had ureter stones, and 2.5% had bladder stones. Furthermore, it was determined that 45% of the stones were composed of calcium oxalate, 35% had calcium phosphate stones, 14.2% had uric acid stones, and 13.3% had cystine stones. In 52% of the cases, extracorporeal shock wave lithotripsy was performed, and 71% underwent surgical treatment.
Conclusion:
Metabolic evaluation and stone analysis should be performed to prevent future recurrences in children with urinary stone disease and lifelong follow-up should be emphasized.
... The plant is broadly utilized as a part of urinary issue like Ashmari (Urinary calculi), Mootrakrichra (Dysuria), Mootravikara and so on by a large portion of the Ayurveda and Siddha specialists in southern India, for the sake of Pashanabheda. [60] [61][62][63][64] Reported Phytochemicals Chemical constituents from this plant are bryophyllol, bryophollone, bryophollenone, bryophynol and two homologous phenanthrene subsidiaries 2(9-decenyl)phenanthrene (I) and 2-(undecenyl) -phenanthrene (II) from leaves; 18α-oleanane, ψ-taraxasterol, α-and βamyrins and their acetic acid derivations were separated. Powerful cytotoxic mixes bersaldegenin-1, 3, 5-orthoacetate and bufadienolidebryophyllin B were likewise disengaged. ...
Medicinal plants may serve as a vital source of potentially advantageous new compounds for the development of effective therapy to action an array of kidney problems. Abounding herbs accept been accurate to be accomplishing as nephroprotective agents while abounding added are claimed to be nephroprotective but there is abridgement of any such accurate affirmation to abutment such claims. Developing a satisfactory herbal therapy to treat serve renal disorders requires systematic investigation of backdrop like acute renal failure, nephritic syndrome and chronic interstitial nephritis. Herbal medicines acquire alleviative backdrop due to the presence of their chemical components. An amount of extracts of accustomed articles and comestible antioxidants accept been appear to appearance careful furnishings adjoin nephrotoxicity. Following herbal drugs accept apparent their almighty nephroprotective aftereffect due their antioxidant, diuretic, anti-inflammatory, antispasmodic properties. The present review is aimed to elucidate the list of nephroprotective medicinal plants, which are scientifically proved in treating renal disorders.
... La proportion d'anomalies métaboliques dans notre étude est similaire à celle d'autres études européennes [7]. Cette proportion est extrêmement variable (5 à 84 %) selon les séries dans d'autres parties du monde [8,19]. Le nombre de lithiases métaboliques n'a probablement pas réellement augmenté mais la recherche plus systématique et plus efficace d'une cause métabolique a sans doute induit une augmentation apparente. ...
Objectives
Urolithiasis is rare in children, but the incidence has increased over the past few decades. This study aims at describing the clinical and biochemical characteristics, etiology, and treatment of urolithiasis in children.
Methods
This was a retrospective study of all children under 16 years of age seen at the Bordeaux University Children's Hospital with a diagnosis of urolithiasis. The diagnosis was confirmed either radiologically or clinically by the expulsion of the stone.
Results
A total of 186 children with a diagnosis of urolithiasis between 1994 and 2012 were included. The median age at diagnosis was 7.4 years. The male-to-female ratio was 1.9. The estimated annual incidence was around 5.5/100,000 children under 15 years of age in the past 5 years. The main presenting feature was nonspecific abdominal pain (71%). Metabolic calculi accounted for 48% of the patients with idiopathic hypercalciuria as the main cause. Genetic diseases accounted for 15% of cases. The proportion of infectious calculi was estimated at 33% and decreased in the past two decades. Stone fragments were sent for analysis in 86 children, and calcium oxalate was the major component (37%), followed by calcium phosphate (33%), purine (9%), and struvite (8%). At least 26% of patients experienced recurrence of stone passage.
Conclusion
This retrospective study highlighted changes in characteristics of pediatric urolithiasis over time. Childhood-onset urolithiasis requires complete etiological work-up so that a metabolic cause with a high risk of recurrence does not go unrecognized.
... La proportion d'anomalies métaboliques dans notre e ´tude est similaire a ` celle d'autres e ´tudes européennes [7] . Cette proportion est extrêmement variable (5 a ` 84 %) selon les séries dans d'autres parties du monde [8,19]. Le nombre de lithiases métaboliques n'a probablement pas réellement augmenté mais la recherche plus systématique et plus efficace d'une cause métabolique a sans doute induit une augmentation apparente. ...
OBJECTIVES:
Urolithiasis is rare in children, but the incidence has increased over the past few decades. This study aims at describing the clinical and biochemical characteristics, etiology, and treatment of urolithiasis in children.
METHODS:
This was a retrospective study of all children under 16 years of age seen at the Bordeaux University Children's Hospital with a diagnosis of urolithiasis. The diagnosis was confirmed either radiologically or clinically by the expulsion of the stone.
RESULTS:
A total of 186 children with a diagnosis of urolithiasis between 1994 and 2012 were included. The median age at diagnosis was 7.4 years. The male-to-female ratio was 1.9. The estimated annual incidence was around 5.5/100,000 children under 15 years of age in the past 5 years. The main presenting feature was nonspecific abdominal pain (71%). Metabolic calculi accounted for 48% of the patients with idiopathic hypercalciuria as the main cause. Genetic diseases accounted for 15% of cases. The proportion of infectious calculi was estimated at 33% and decreased in the past two decades. Stone fragments were sent for analysis in 86 children, and calcium oxalate was the major component (37%), followed by calcium phosphate (33%), purine (9%), and struvite (8%). At least 26% of patients experienced recurrence of stone passage.
CONCLUSION:
This retrospective study highlighted changes in characteristics of pediatric urolithiasis over time. Childhood-onset urolithiasis requires complete etiological work-up so that a metabolic cause with a high risk of recurrence does not go unrecognized.
Copyright © 2014 Elsevier Masson SAS. All rights reserved.
... (Amaranthaceae) is a herbaceous perennial weed growing wild in the tropical regions and western ghats of India. Aerva lanata has been claimed to be useful as diuretic, anthelmintic, antidiabetic, expectorant and hepatoprotective, Antimicrobial and cytotoxicity activity, urolithiasis and anti-inflammatory activity of Aerva lanata has been reported [8][9]. ...
The aim of this study is to test the efficacy of different fractions of Aerva lanata extract for their antimicrobial activity and analyze the influence of fractions on the virulent factors of microorganisms. The whole plant Aerva lanata (L) Juss.Ex. Schlt, commonly known as Pashanabheda used by various Ayurvedic physicians for various diseased conditions traditionally. As this plant is widely available in Western Ghats and no scientific reports on the antimicrobial potency of the plant fraction/s reported till date, we have conducted this study with an objective that the results will enlarge the existing knowledge. In this study the whole plant was subjected for extraction with hydroalcohol followed by fractionation with different solvents based on their polarities. Urolithiasis is found to be one among the top five critical conditions responsible for urinary tract infections worldwide and as this plant is used as Pashanabheda traditionally, we are aimed at identifying the antimicrobial potency of this plant which shall help to substantiate the traditional claims of this plant in nurolithiasis treatment. We found that different fractions of this plant have produced promising antimicrobial results against
... (Amaranthaceae) is a herbaceous perennial weed growing wild in the tropical regions and western ghats of India. Aerva lanata has been claimed to be useful as diuretic, anthelmintic, antidiabetic, expectorant and hepatoprotective, Antimicrobial and cytotoxicity activity, urolithiasis and anti-inflammatory activity of Aerva lanata has been reported [8][9]. ...
In this present study Aerva lanata (L), the whole plant commonly known as Pashanabheda, which is used by various Ayurvedic physicians traditionally for various diseases and widely available in Western Ghat is selected. The whole plant is subjected to extraction with hydro alcohol (ethanol 90%) followed by fractionation with different solvents based on their polarities such as Petroleum ether, Dichloromethane, Ethyl acetate and n-Butanol. Later these fractions are analyzed by UV-VIS, IR and HPTLC study and this study has revealed the presence of important functional groups in these fractions
Plants contain a diverse group of highly valuable and readily available resource of bioactive metabolites viz. Alkaloids, tannins, essential oils and flavonoids. According to World Health Organization has estimated that about 80% of the population in developing countries are unable to afford drugs and rely on traditional medicines especially those that are plan based such as India, Srilanka, Bangladesh, China and Japan. Exploration of the chemical constituents of the plants and pharmacological screening may provide us the basis for developing the lead for development of novel agents. Herbs have provided us some of the very important life savings drugs used in armamentarium of modern medicine, present study helps to know that poly herbal formulations are safe and effective and show synergetic actions. There is a much research is in need for future prospects in drug development and dosage design from natural sources having Antimicrobial activity.
Plants contain a diverse group of highly valuable and readily available resource of bioactive metabolites viz. Alkaloids, tannins, essential oils and flavonoids. According to World Health Organization has estimated that about 80% of the population in developing countries are unable to afford drugs and rely on traditional medicines especially those that are plan based such as India, Srilanka, Bangladesh, China and Japan. Exploration of the chemical constituents of the plants and pharmacological screening may provide us the basis for developing the lead for development of novel agents. Herbs have provided us some of the very important life savings drugs used in armamentarium of modern medicine, present study helps to know that poly herbal formulations are safe and effective and show synergetic actions. There is a much research is in need for future prospects in drug development and dosage design from natural sources having Antimicrobial activity.
Background Recent studies have reported an increasing prevalence of stone diseases (urolithiasis and cholelithiasis) worldwide. However, studies that evaluate the occurrence of stone diseases in Ethiopia are scarce. The objective of this study was to determine trends in the incidence of stone diseases, and the associated comorbidities in Ethiopia during the last 13 years. Methods Thirteen years retrospective data were collected from medical records (Log Books and Electronic Databases) at St. Paulos Tertiary Referral Hospital, September 2005/2006 to 2017/2018. A total of 32,370 surgically treated patients were included in the study. Open surgical treatments related to stone diseases were identified via a thorough review of patient medical records. Data were analyzed using Graph Pad Prism 6 Software. P value
