Compliance for perigastric and extra-perigastric lymph node stations.

Compliance for perigastric and extra-perigastric lymph node stations.

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Simple Summary Since nodal metastasis is the main pattern for gastric cancer (GC) metastasis, lymph node (LN) dissection is essential for accurate staging and improving prognosis. However, debates exist regarding the necessity of No. 12a LN dissection (LND) in D2 gastrectomy. Moreover, the compliance rate for No. 12a LND in practice is low. To expl...

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Context 1
... shown in Table 1, the lowest compliance rate was reported for the dissection of station 12a LNs. The No. 12a LND compliance rate of the whole study cohort was 37.1% (1035/2788). ...
Context 2
... PSM, the No. 12a LND compliance group still had a better OS than the No. 12a LND noncompliance group (median OS 146.3 vs. 85.7 months, 5-year OS 64.5% vs. 56.4%, p < 0.001, Figure 2B (Table S1). ...

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... Proper dissection of station 12a has been associated with improved overall survival. 38 ICG lymphography has been previously reported as a useful tool to complete lymphadenectomy at the splenic hilum 35,39 and infrapyloric area. 19 This technology could also motivate surgeons to move safely from D1þ to D2 dissection due to the clear visualization of the fluorescent LNs and their boundaries with the surrounding tissue. ...
... From the perspective of postoperative recovery, URY is more suitable for GC patients than RY. In addition, it is crucial to consider whether URY has afferent loop recanalization and the impact of anastomosis on long-term prognosis [34]. ...
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Background Uncut Roux-en-Y (URY) effectively alleviates the prevalent complexities connected with RY, such as Roux-en-Y stasis syndrome (RSS). Nevertheless, for gastric cancer (GC) patients, it is still controversial whether URY has an impact on long-term prognosis and whether it has fewer afferent loop recanalization. Therefore, compare whether URY and RY have differences in prognosis and long-term complications of GC patients undergoing totally laparoscopic gastrectomy (TLG). Methods We analyzed the data of patients who underwent TLG combined with digestive tract reconstruction from dual-center between 2016 and 2022. Only patients undergoing URY and RY were selected for analysis. Relapse-free survival (RFS) and overall survival (OS) were estimated. Bias between the groups was reduced by propensity score matching (PSM). The Cox proportional hazard regression model was used to further analyze the influence of URY on prognosis. Results Two hundred forty two GC patients were enrolled. The URY had significantly shorter operation time, liquid food intake time, and in-hospital stays than the RY (P < 0.001). The URY had fewer long-term and short-term postoperative complications than the RY, especially with regard to RSS, reflux esophagitis, and reflux gastritis. The 3-year and 5-year OS of the URY group and the RY group before PSM: 87.5% vs. 65.6% (P < 0.001) and 81.4% vs. 61.7% (P = 0.001). PSM and Cox multivariate analysis confirmed that compared to RY, URY can improve the short-term and long-term prognosis of GC patients. Conclusion TLG combined with URY for GC, especially for advanced, older, and poorly differentiated patients, may promote postoperative recovery and improve long-term prognosis.
... From the perspective of postoperative recovery, URY is more suitable for GC patients than RY. In addition, it should be noted whether URY has input loop recanalization and the impact of anastomosis on long-term prognosis [34]. ...
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