Comparison of long-term neurodevelopmental outcomes among no infection, infection without invasive fungal infection (NFI) and invasive fungal infection (IFI) groups.

Comparison of long-term neurodevelopmental outcomes among no infection, infection without invasive fungal infection (NFI) and invasive fungal infection (IFI) groups.

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Background Invasive fungal infection (IFI) is associated with significant mortality and morbidity among preterm infants but there has been no population-based study of long-term neurodevelopmental outcomes. The objective of this study was to examine population-based incidence trends as well as mortality, short term in-hospital morbidity and long-te...

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... infants with no infection, NFI and IFI, the incidence of the primary outcome (sNDI) was 14.84%, 21.63% and 44.26% respectively, while mortality was 22.25%, 25.35% and 50% respectively. The weight, length and head circumference were correspondingly inverse (i.e., decreasing) among infants with no infection, NFI and IFI (Table 3). These differences persisted after adjustment for confounders using multivariable regression analyses ( Table 4). ...