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Background
Skin and subcutaneous disease is the fourth-leading cause of the nonfatal disease burden worldwide and constitutes one of the most common burdens in primary care. However, there is a severe lack of dermatologists, particularly in rural Chinese areas. Furthermore, although artificial intelligence (AI) tools can assist in diagnosing skin d...
Contexts in source publication
Context 1
... comparison between the experimental results of Xy-SkinNet and the average performance of dermatologists is shown in Table 2. The receiver operating characteristic (ROC) curve of the model for six types of diseases is shown in Figure 4, in which the performance of each dermatologist is also plotted. ...Context 2
... receiver operating characteristic (ROC) curve of the model for six types of diseases is shown in Figure 4, in which the performance of each dermatologist is also plotted. As the results showed (Table 2), Xy-SkinNet achieved a top 1 accuracy of 64.75%, while the average performance of the dermatologists was 62.13%. Moreover, Xy-SkinNet outperformed the dermatologists in terms of the top 3 accuracy, where Xy-SkinNet achieved an accuracy of 84.77%, while the dermatologists achieved an accuracy of 78.15%. ...Context 3
... comparison of accuracies (%) on six different skin diseases between Xy-SkinNet and the average of dermatologists with different levels in the external data set provided by dermatologists are shown in Table 2. Xy-SkinNet achieved a top 1 accuracy of 64.75%, while the average performance of the dermatologists was 62.13%. ...Similar publications
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Zusammenfassung
Der Einsatz von künstlicher Intelligenz (KI) setzt sich in den verschiedensten Bereichen der Medizin immer schneller durch. Dennoch fehlt vielen medizinischen Kollegen das technische Grundverständnis für die Funktionsweise dieser Technologie, was ihre Anwendung in Klinik und Forschung stark einschränkt. Daher möchten wir in dieser Übersichtsarbeit die Funktionsweise und Klassifizierung der KI am Beispiel des Melanoms erörtern, um ein Verständnis für die Technologie hinter der KI zu schaffen. Dazu werden ausführliche Illustrationen verwendet, die die Technologie schnell erklären. Bisherige Übersichten konzentrieren sich eher auf die potenziellen Anwendungen der KI und verpassen die Gelegenheit, ein tieferes Verständnis für die Materie herauszuarbeiten, das für die klinische Anwendung so wichtig ist. Das maligne Melanom ist zu einer erheblichen Belastung für die Gesundheitssysteme geworden. Bei frühzeitiger Entdeckung ist eine bessere Prognose zu erwarten, weshalb das Hautkrebs‐Screening immer populärer und von den Krankenkassen unterstützt wird. Die Zahl der Fachärzte ist jedoch begrenzt, was ihre Verfügbarkeit einschränkt und zu längeren Wartezeiten führt. Daher müssen innovative Ideen umgesetzt werden, um die notwendige Versorgung zu gewährleisten. Das maschinelle Lernen bietet die Möglichkeit, Melanome auf Bildern zu erkennen, und zwar auf einem Niveau, das mit dem von erfahrenen Dermatologen – unter optimierten Bedingungen – vergleichbar ist.
The use of artificial intelligence (AI) continues to establish itself in the most diverse areas of medicine at an increasingly fast pace. Nevertheless, many healthcare professionals lack the basic technical understanding of how this technology works, which severely limits its application in clinical settings and research. Thus, we would like to discuss the functioning and classification of AI using melanoma as an example in this review to build an understanding of the technology behind AI. For this purpose, elaborate illustrations are used that quickly reveal the technology involved. Previous reviews tend to focus on the potential applications of AI, thereby missing the opportunity to develop a deeper understanding of the subject matter that is so important for clinical application. Malignant melanoma has become a significant burden for healthcare systems. If discovered early, a better prognosis can be expected, which is why skin cancer screening has become increasingly popular and is supported by health insurance. The number of experts remains finite, reducing their availability and leading to longer waiting times. Therefore, innovative ideas need to be implemented to provide the necessary care. Thus, machine learning offers the ability to recognize melanomas from images at a level comparable to experienced dermatologists under optimized conditions. K E Y W O R D S artificial intelligence, artificial neural network, machine learning, Melanoma, teledermatology
Artificial intelligence (AI) is a field of computer science that involves the development of programs designed to replicate human cognitive processes and the analysis of complex data. In dermatology, which is predominantly a visual‐based diagnostic field, AI has become increasingly important in improving professional processes, particularly in the diagnosis of psoriasis. In this review, we summarized current AI applications in psoriasis: (i) diagnosis, including identification, classification, lesion segmentation, lesion severity and area scoring; (ii) treatment, including prediction treatment efficiency and prediction candidate drugs; (iii) management, including e‐health and preventive medicine. Key challenges and future aspects of AI in psoriasis were also discussed, in hope of providing potential directions for future studies.
Background
Psoriasis is one of the most frequent inflammatory skin conditions and could be treated via tele-dermatology, provided that the current lack of reliable tools for objective severity assessments is overcome. Psoriasis Area and Severity Index (PASI) has a prominent level of subjectivity and is rarely used in real practice, although it is the most widely accepted metric for measuring psoriasis severity currently.
Objective
This study aimed to develop an image–artificial intelligence (AI)–based validated system for severity assessment with the explicit intention of facilitating long-term management of patients with psoriasis.
Methods
A deep learning system was trained to estimate the PASI score by using 14,096 images from 2367 patients with psoriasis. We used 1962 patients from January 2015 to April 2021 to train the model and the other 405 patients from May 2021 to July 2021 to validate it. A multiview feature enhancement block was designed to combine vision features from different perspectives to better simulate the visual diagnostic method in clinical practice. A classification header along with a regression header was simultaneously applied to generate PASI scores, and an extra cross-teacher header after these 2 headers was designed to revise their output. The mean average error (MAE) was used as the metric to evaluate the accuracy of the predicted PASI score. By making the model minimize the MAE value, the model becomes closer to the target value. Then, the proposed model was compared with 43 experienced dermatologists. Finally, the proposed model was deployed into an app named SkinTeller on the WeChat platform.
Results
The proposed image-AI–based PASI-estimating model outperformed the average performance of 43 experienced dermatologists with a 33.2% performance gain in the overall PASI score. The model achieved the smallest MAE of 2.05 at 3 input images by the ablation experiment. In other words, for the task of psoriasis severity assessment, the severity score predicted by our model was close to the PASI score diagnosed by experienced dermatologists. The SkinTeller app has been used 3369 times for PASI scoring in 1497 patients from 18 hospitals, and its excellent performance was confirmed by a feedback survey of 43 dermatologist users.
Conclusions
An image-AI–based psoriasis severity assessment model has been proposed to automatically calculate PASI scores in an efficient, objective, and accurate manner. The SkinTeller app may be a promising alternative for dermatologists’ accurate assessment in the real world and chronic disease self-management in patients with psoriasis.
Background
The lack of dark skin images in pathologic skin lesions in dermatology resources hinders the accurate diagnosis of skin lesions in people of color. Artificial intelligence applications have further disadvantaged people of color because those applications are mainly trained with light skin color images.
Objective
The aim of this study is to develop a deep learning approach that generates realistic images of darker skin colors to improve dermatology data diversity for various malignant and benign lesions.
Methods
We collected skin clinical images for common malignant and benign skin conditions from DermNet NZ, the International Skin Imaging Collaboration, and Dermatology Atlas. Two deep learning methods, style transfer (ST) and deep blending (DB), were utilized to generate images with darker skin colors using the lighter skin images. The generated images were evaluated quantitively and qualitatively. Furthermore, a convolutional neural network (CNN) was trained using the generated images to assess the latter’s effect on skin lesion classification accuracy.
Results
Image quality assessment showed that the ST method outperformed DB, as the former achieved a lower loss of realism score of 0.23 (95% CI 0.19-0.27) compared to 0.63 (95% CI 0.59-0.67) for the DB method. In addition, ST achieved a higher disease presentation with a similarity score of 0.44 (95% CI 0.40-0.49) compared to 0.17 (95% CI 0.14-0.21) for the DB method. The qualitative assessment completed on masked participants indicated that ST-generated images exhibited high realism, whereby 62.2% (1511/2430) of the votes for the generated images were classified as real. Eight dermatologists correctly diagnosed the lesions in the generated images with an average rate of 0.75 (360 correct diagnoses out of 480) for several malignant and benign lesions. Finally, the classification accuracy and the area under the curve (AUC) of the model when considering the generated images were 0.76 (95% CI 0.72-0.79) and 0.72 (95% CI 0.67-0.77), respectively, compared to the accuracy of 0.56 (95% CI 0.52-0.60) and AUC of 0.63 (95% CI 0.58-0.68) for the model without considering the generated images.
Conclusions
Deep learning approaches can generate realistic skin lesion images that improve the skin color diversity of dermatology atlases. The diversified image bank, utilized herein to train a CNN, demonstrates the potential of developing generalizable artificial intelligence skin cancer diagnosis applications.
International Registered Report Identifier (IRRID)
RR2-10.2196/34896
