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Clinical symptoms. Splinter hemorrhages discretely visible on the nails of the right hand (circles) were one of the first symptoms presented by the patient.
Source publication
We report a case of a young male who presented with acute limb ischemia after sport. With no prior history of disease, a non-infective endocarditis of the native aortic valve was diagnosed. After surgical valve replacement, the patient suffered from acute myocardial ischemia under phenprocoumon therapy. Anti-coagulant monitoring was subsequently ch...
Context in source publication
Context 1
... 28-year-old male experienced fever and increasing unilateral calf pain after a football game and presented himself to the emergency department the following day. The physical examination showed typical signs of a peripheral arterial occlusion, as well as splinter hemorrhages of the fingernails (Figure 1). The rest of the physical examination was inconspicuous and there were no signs of infection in the otherwise normal blood tests. ...
Citations
... In addition, there is a form of nonbacterial thrombotic endocarditis (NBTE), which has been described primarily in humans (Reid et al., 2020;Vinogradova, 2010). NBTE is characterized by sterile vegetations on the valve leaflets, mainly consisting of fibrin, platelets, and inflammatory cells, but in smaller quantities than IE. ...
Infectious endocarditis (IE) is a contagious polyposis ulcerative inflammation of the endocardium, accompanied by lesions of the heart valve apparatus and endothelium by various pathogenic and opportunistic pathogens. Mainly mitral and aortic valves are affected, less often - tricuspid valve. The purpose of this study was to report two cases of IE in cats. Due to the low prevalence of the disease in cats, there is no clear diagnostic algorithm, so the diagnostic search is complicated. In both cases, autonomic lesions of the heart valve apparatus were observed. In the first clinical case, we could hardly diagnose the disease because of its rapid progression: initial echocardiogram result was normal, but after 48 hours, the cat's condition became much worse, and 18 hours later, it died. In the second case, histopathological examination confirmed an infectious inflammatory process of the endocardium and myocardium of unclear genesis. However, the presence of lower respiratory tract infection and the absence of additional laboratory tests, such as bacterial blood culture and PCR diagnosis, limited us in proposing a hypothesis about the origin and etiology of IE.
Described herein is a 48-year-old woman with metastatic ovarian cancer who developed aortic regurgitation considered clinically to be the result of infective endocarditis but operative resection of the three aortic valve cusps disclosed the valve lesions to be typical of non-bacterial thrombotic endocarditis (NBTE). Aortic regurgitation as a consequence of NBTE is rare but at least 9 cases have been reported previously.
