Figure 2 - uploaded by Bruno Caramelli
Content may be subject to copyright.
Classification, target, and half-life of antiplatelet drugs.

Classification, target, and half-life of antiplatelet drugs.

Source publication
Article
Full-text available
Patients undergoing cataract surgery are generally elderly, and many take drugs with systemic effects. The surgeon must be aware of the risks of continuing or discontinuing such medications perioperatively. Antiplatelet drugs and anticoagulants, prescribed to reduce the incidence of thromboembolic events, are often used in this population. This pap...

Contexts in source publication

Context 1
... are the first-line of antithrombotic therapy to treat and prevent acute ischemic syndromes (9,12) . Figure 2 shows the classification, target, and half-life of Ap drugs. ...
Context 2
... are the first-line of antithrombotic therapy to treat and prevent acute ischemic syndromes (9,12) . Figure 2 shows the classification, target, and half-life of Ap drugs. ...

Citations

... For patients at extremely high cardiovascular from suspension of APT and DOACs, the recommendation is to perform the intervention without suspending the medication and employing topical anesthesia and sedation. [393][394][395][396][397][398][399] Recommendation 8.5.1 ...
... Phacoemulsification cataract surgeries and intraocular lens implantations for which APT suspension is contraindicated due to high risk of cardiovascular events may be performed under topical anesthesia and sedation (I/A). [393][394][395][396][397][398][399] ...
... APT and/or anticoagulants should be restarted on the day following the procedure (I/A). [393][394][395][396]398 Recommendation 8. ...
... Also, a 2012 study found that the risks for early agerelated macular degeneration (AMD) and wet late AMD are associated with frequent aspirin use, and the risk increases with greater aspirin consumption. [7,8] ...
... Large proportion of patients for cataract surgery belong to elderly population, who also have age related comorbidities. 1 Antiplatelet agents and anticoagulants are used to minimize the risk of thromboembolic events in coronary heart disease or other vascular diseases. Some consider discontinuation of anti-thrombotic therapy as routine to minimize the risk of bleeding during surgery, it may be potentially harmful for those with higher risk of thrombosis. ...
Article
Full-text available
To ascertain whether to stop or continue aspirin before cataract surgery. Prospective observational study from July 2018 to June 2019. Information on pre-existing medical conditions like cardiac disease/stroke & use of Aspirin was obtained from patients posted for cataract surgery. Physical examination was done by physician & decided whether aspirin has to be stopped before surgery. Intra-operative and post-operative outcomes were recorded. SPSS 20.0 by using descriptive statistics i.e. only frequency and percentage. Out of 64 patients, 38 discontinued aspirin and 26 continued. In the group of patients who discontinued aspirin, 2 had bleeding complication in the form of bleeding from cut ends of conjunctiva. Where as in the group who continued aspirin 4 patients had bleeding complication. No thromboembolic events were recorded in both the groups. The risk of medical & ophthalmic events surrounding cataract surgery were so low that absolute differences in risk associated with changes in Aspirin use were minimal.