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Classification of cholestasis according to biochemical data, image information obtained by abdominal echography, endoscopic retrograde cholangiopancreatography (ERCP) and computed tomography scan (CT-Scan), and the anatomical location of the cause. ALP: alkaline phosphatase; GGT: γ-glutamyltransferase

Classification of cholestasis according to biochemical data, image information obtained by abdominal echography, endoscopic retrograde cholangiopancreatography (ERCP) and computed tomography scan (CT-Scan), and the anatomical location of the cause. ALP: alkaline phosphatase; GGT: γ-glutamyltransferase

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Figure 1. Classification of cholestasis according to biochemical data,...
Figure 2. Localization at the apical and basolateral plasma membrane of...
Figure 3. Diagnostic algorithm and suggested treatment of most frequent...
Plasma membrane transporters and channels involved in hepatobiliary...
Plasma membrane transporters and channels involved in hepatobiliary...
Etiopathogenesis and pathophysiology of cholestasis
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  • Oct 2022
Normal hepatobiliary function depends on an adequate bile flow from the liver through the biliary tree to the gallbladder, where bile is stored and concentrated, and from the gallbladder to the duodenum when it is required for the digestive process. Interruption of this secretory function results in partial or complete cholestasis, which is accompa...
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Context 1
... biliary secretion is commonly diagnosed following well-established clinical practice algorithms (see, for instance, the one shown in Figure 1). Elevated serum bile acids are the most sensitive marker of cholestasis. ...