Choroid plexus of the 4 ventricle with numerous elongated villi lined by a single epithelial layer supported on a fibrovascular stroma. Hematoxylin and eosin. Bar = 200 μm. 

Choroid plexus of the 4 ventricle with numerous elongated villi lined by a single epithelial layer supported on a fibrovascular stroma. Hematoxylin and eosin. Bar = 200 μm. 

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A 2-day-old Mangalarga Marchador colt was presented with clinical signs of severe mental depression, unable to stand, and lacking a suckling reflex. Despite intensive medical care, there was no improvement and the colt died 30 hours later. Gross lesions were characterized by aplasia of the cerebellar vermis, cystic dilatation of the fourth ventricl...

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... vermis was present at the level of the medullary canal. This portion of the cerebellum showed moderate reduction of neurons in the granular layer. The enlarged choroid plexus was characterized by numerous long villous/papillary projections lined by a single layer of cuboidal cells anchored on a basement membrane and fibrovascular stromal (Fig. 4). The cuboidal cells lining the villous projections were identical to normal choroidal projections and it was interpreted as hyperplasia. On histological examination, lung lesions were characterized by marked multifocal neutrophilic infiltrates associated with variably sized eosinophilic dropplets (milk) within bronchial and bronchiolar ...

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