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Cholesteatoma characteristics classified sec. STAMCO classification associated with peri-operative complications in patient’s cohort (percentage). STAMCO CLASSIFICATION S. §: Involvement of difficult access sites (supratubal recess, sinus tympani), T: involvement of tympanic cavity, A: involvement of attic/epitympanic space, M: involvement of mastoid and antrum, C: complication status, O: ossicular status at the beginning of the surgery, § 3 patients had both S = 1 and S = 2
Source publication
Purpose
To compare the relationship between the variable “complication” and the other variables of middle ear cholesteatoma classifications (STAMCO, ChOLE, and SAMEO-ATO).
Methods
Retrospective study of 110 patients that underwent 132 middle ear surgeries between the 1 January 2012 and the 31 December 2019 for chronic otitis with cholesteatoma cla...
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Objective:
To describe national trends in cholesteatoma management.
Study design and setting:
Retrospective analysis Optum Clinformatics® Database from 2003 to 2019.
Patients:
16,179 unique adult and pediatric patients who received cholesteatoma surgery.
Interventions and main outcome measures:
Patients were categorized into three groups by...
Citations
... Hearing loss was common due to the erosion of the ossicles. The cholesteatoma can extend to the face, brain, and the neck if left untreated [50]. When becoming infected, the cholesteatoma can grow faster. ...
Biomaterials play an integral role in treatment of external auditory canal (EAC) diseases. Regarding the special anatomic structure and physiological characteristics of EAC, careful selection of applicable biomaterials was essential step towards effective management of EAC conditions. The bioactive materials can provide reasonable biocompatibility, reduce risk of host pro-inflammatory response and immune rejection, and promote the healing process. In therapeutic procedure, biomaterials were employed for covering or packing the wound, protection of the damaged tissue, and maintaining of normal structures and functions of the EAC. Therefore, understanding and application of biomaterials was key to obtaining great rehabilitation in therapy of EAC diseases. In clinical practice, biomaterials were recognized as an important part in the treatment of different EAC diseases. The choice of biomaterials was distinct according to the requirements of various diseases. As a result, awareness of property regarding different biomaterials was fundamental for appropriate selection of therapeutic substances in different EAC diseases. In this review, we firstly introduced the characteristics of EAC structures and physiology, and EAC pathologies were summarized secondarily. From the viewpoint of biomaterials, the different materials applied to individual diseases were outlined in categories. Besides, the underlying future of therapeutic EAC biomaterials was discussed.
... Whereas many studies document complications from the records, e.g., a study conducted in Saudi Arabia found that 105 patients (10.2%) experienced postoperative problems of which minor complications were the most common (9.5%) [16], and many other studies elsewhere [12,16,17]. In relation to gender and age, one study [18] reported that the female gender has a protective effect against intraoperative complications as well as patient age which was found to be correlated with a higher incidence of intraoperative complications [18]. In our humble opinion, this omission may be attributable to reporting bias. ...
... Whereas many studies document complications from the records, e.g., a study conducted in Saudi Arabia found that 105 patients (10.2%) experienced postoperative problems of which minor complications were the most common (9.5%) [16], and many other studies elsewhere [12,16,17]. In relation to gender and age, one study [18] reported that the female gender has a protective effect against intraoperative complications as well as patient age which was found to be correlated with a higher incidence of intraoperative complications [18]. In our humble opinion, this omission may be attributable to reporting bias. ...
Background:
Cholesteatoma is described as the accumulation of squamous epithelium and keratinocytes within and around the middle ear cleft. There is a paucity of information regarding demographic and treatment outcomes for cholesteatoma in Saudi Arabia. An evaluation of the prevalence of comorbidities, complications and associations, of surgical treatment and demographics in the Qassim region was conducted.
Methods:
This was a six-year retrospective review of patients treated for cholesteatoma at a private health facility, from August 2016 to July 2022. Data for age, gender, nationality, presence of comorbidities, type of surgery, type of anesthesia, and associated complications were collected from the electronic medical records and analyzed with Statistical Package for Social Sciences software.
Results:
A total of 60 participants records were retrieved. The average age of the study population was ([43.2 ±SD] 21.8) years. There was a slightly higher male preponderance (males 51.7% and females 48.3%). Hypertension was the most commonly reported comorbidity (31.7%), followed by diabetes mellitus (25%). Age and gender were not statistically significantly associated with type of surgery or complications.
Conclusion:
Demographic variables were not significantly associated with clinical correlates, however, further studies with larger sample sizes, robust clinical information, and long-term follow-up are required.
... (2021 г.), показана значимость системы SAMEO-ATO для определения риска развития осложнений хирургического лечения. В данном исследовании проанализированы результаты 132 операций по поводу ХСУ у 110 пациентов, осложнения выявлены в 17% случаев (чаще всего -фистула латерального полукружного канала, реже -фистула верхнего полукружного канала и др.) [28]. По данным многомерного регрессионного анализа с риском развития осложнений статистически значимо ассоциированы оценка по SAMEO-ATO O1 (2 vs 1), SAMEO-ATO T (3 vs 1 или 2) и SAMEO-ATO O2 (S-vs F-) [28]. ...
... В данном исследовании проанализированы результаты 132 операций по поводу ХСУ у 110 пациентов, осложнения выявлены в 17% случаев (чаще всего -фистула латерального полукружного канала, реже -фистула верхнего полукружного канала и др.) [28]. По данным многомерного регрессионного анализа с риском развития осложнений статистически значимо ассоциированы оценка по SAMEO-ATO O1 (2 vs 1), SAMEO-ATO T (3 vs 1 или 2) и SAMEO-ATO O2 (S-vs F-) [28]. ...
Middle ear cholesteatoma (MEC) is a common problem of modern otology. The European Academy of Otology and Neurootology in cooperation with the Japanese Otological Society (EAONO/JOS) published consensus recommendations on the definition, classification and stages of MEC in 2017. In 2018, the classification of middle ear surgery was presented under the auspices of the International Otology Outcome Group. The leading problem of MEC surgery remains the high recurrence rate, which ranges from 5 to 32% depending on the type of surgical intervention. The main purpose of this article is to describe the new EAONO/JOS classification of MEC and SAMEO-ATO middle ear surgical interventions with an analysis of their possible clinical significance in determining the risk of cholesteatoma recurrence as well as the prognosis for hearing recovery after surgery.
Background
Diffusion-weighted imaging (DWI) has become an important tool for the detection of cholesteatoma. The purpose of this study was to explore the value of 2D BLADE turbo gradient- and spin-echo imaging (TGSE BLADE) DWI in the quantitative diagnosis of recurrent temporal bone cholesteatoma (CS).
Methods
From March 2018 to October 2021, 67 patients with suspected recurrence of temporal bone CS after assessment by clinical otorhinolaryngologists who had undergone previous ear surgery for CS were prospectively evaluated by magnetic resonance imaging (MRI). Two radiologist assessed images independently. Quantitative parameters such as signal intensity ratio (SIR) calculated using, as a reference, the inferior temporal cortex (SIRT) and the background noise (SIRN), apparent diffusion coefficient (ADC) value, and ADC ratio (with pons as reference) measured on TGSE BLADE sequences were assessed. Using receiver operating characteristic (ROC) curve analysis, the optimal threshold and diagnostic performance for diagnosing recurrent CS were determined. Pair-wise comparison of the ROC curves was performed using the area under the ROC curve (AUC).
Results
Finally, 44 patients were included in this study, including 25 CS and 19 non-cholesteatoma (NCS). Mean SIRT and mean SIRN on TGSE BLADE DWI were significantly higher for CS than NCS lesions (p < 0.001). Meanwhile, mean ADC values and mean ADC ratios on ADC maps were significantly lower in the CS group than in the NCS group (p < 0.001). According to ROC analysis, the diagnostic efficacy of quantitative parameters such as SIRT (AUC = 0.967), SIRN (AUC = 0.979), ADC value (AUC = 1.0), and ADC ratio (AUC = 0.983) was significantly better than that of qualitative DWI (AUC = 0.867; p = 0.007, 0.009, 0.011 and 0.037, respectively).
Conclusions
Residual/recurrent temporal bone CS can be accurately detected using quantitative evaluation of TGSE BLADE DWI.
Background: Diffusion-weighted imaging (DWI) has become an important tool for the detection of cholesteatoma. The purpose of this study was to explore the value of 2D BLADE turbo gradient- and spin-echo imaging (TGSE BLADE) DWI in the quantitative diagnosis of recurrent temporal bone cholesteatoma (CS).
Methods: From March 2018 to October 2021, 67 patients with suspected recurrence of temporal bone CS after assessment by clinical otorhinolaryngologists who had undergone previous ear surgery for CS were prospectively evaluated by magnetic resonance imaging (MRI). Two radiologist assessed images independently. Quantitative parameters such as signal intensity (SI), signal intensity ratio (SIR), apparent diffusion coefficient (ADC) value, and ADC ratio measured on TGSE BLADE sequences were assessed. Using receiver operating characteristic (ROC) curve analysis, the optimal threshold and diagnostic performance for diagnosing recurrent CS were determined. Pair-wise comparison of the ROC curves was performed using the area under the ROC curve (AUC).
Results: Finally, 44 patients were included in this study, including 25 CS and 19 non-cholesteatoma (NCS). Mean SI and mean SIR on TGSE BLADE DWI were significantly higher for CS than NCS lesions (p<0.001). Meanwhile, mean ADC values and mean ADC ratios on ADC maps were significantly lower in the CS group than in the NCS group (p<0.001). According to ROC analysis, the diagnostic efficacy of quantitative parameters such as SI (AUC = 0.983), SIR (AUC = 0.967), ADC value (AUC = 1.0), and ADC ratio (AUC = 0.983) was significantly better than that of qualitative DWI (AUC = 0.867; p = 0.025, 0.026, 0.011 and 0.037, respectively).
Conclusions: Residual/recurrent temporal bone CS can be accurately detected using quantitative evaluation of TGSE BLADE DWI.
