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A 68-year-old Caucasian man presented with gross hematuria and oral mucosal bleeding. The patient was known to have an anterior mediastinal mass, highly suspicious for thymoma, which was incidentally identified on imaging, 8 years prior. The patient then declined treatment and was lost to follow-up. On presentation, imaging re-demonstrated the ante...
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... studies re-demonstrated the left anterior mediastinal mass that was known 8 years prior to presentation, on both Dvir et al J Hematol. 2019;000(000):000-000 chest X-ray (Fig. 4) and on non-contrast CT (Fig. 5). CT chest, abdomen and pelvis showed interval enlargement of anterior mediastinal mass, measuring 7.8 × 6.9 cm, from previously measured 4.7 × 4.3 cm on positron emission tomography/CT (PET/CT) done 8 years prior. These findings likely represented a thymoma versus potential invasive ...
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Citations
A 71-year-old female with type B3 thymoma developed severe aplastic anemia. Anti-thymocyte globulin was administered with glucocorticoids and cyclosporin A as the treatment for aplastic anemia. Computed tomography scan revealed that thymoma apparently shrank and remained without regrowth for at least 7 months. As previously reported, glucocorticoid has therapeutic effects on thymoma especially with abundant lymphocytes. Anti-thymocyte globulin also depletes peripheral lymphocytes, but its efficacy in the treatment of thymoma is unknown. Anti-thymocyte globulin and glucocorticoids may have cooperated with each other in reducing thymoma in our case. More cases should be accumulated to elucidate the effects of anti-thymocyte globulin on thymoma.
