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Despite the significant development of diagnostic procedures and therapeutic options in past few decades, glaucoma is still highly prevalent and represents one of the leading causes of blindness in the world due to progressive and irreversible changes in optic nerve. Detection of carbonic anhydrase as a suitable target for the control of intraocula...
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In this study, inhibition of human carbonic anhydrase (h CAI) enzyme was investigated in four different organic synthesis compounds. Two of these compounds are [(4-amino-3-phenyl-5-p-tolyl-4H-1,2,4-triazole) (1) and (2,5-diphenyl-1,3,4-oxadiazol) (2)] was previously synthesized by our group, while the other two were newly synthesized [(4-methyl-N-(...
