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Chemical structure of Vitamin C

Chemical structure of Vitamin C

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Figure 1. Chemical structure of Vitamin C
Figure 2. Chemical structure of vitamin B12
Figure 3.a: UV-absorbance spectra of BSA with different concentrations...
Figure 4.a: The plot of 1/(A-Ao) vs. 1/L for BSA with different...
+3 Figure 5.a: Fluorescence emission spectra of BSA in the absence and...
E-ISSN: 2249 -1929 Chemical, Biological and Physical Sciences An International Peer Review E-3 Journal of Sciences Available online atwww.jcbsc.org Section C: Physical Sciences CODEN (USA): JCBPAT Research Article 256
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  • May 2018
The interaction between vitamin C and vitamin B12 with bovine serum albumin has been investigated. The binding mechanism was studied by UV-absorption and fluorescence spectroscopy. From spectral analysis both vitamins showed strong ability to quench the intrinsic fluorescence of BSA through a static quenching procedure. The binding constants are es...
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Context 1
... are vital as they play integral roles in hundreds of life-sustaining biochemical reactions and are also catalysts for all reactions using proteins, fats and carbohydrates for energy, growth and cell maintenance 1 . Vitamin B12 (Fig.1) is needed in many body processes; in the manufacture and the maintenance of red blood cells, the synthesis of DNA, stimulate of nerve cells, the growth promotion and energy releases and the proper Serum albumin is the most abundant protein in blood plasma, it serve as depot proteins and transport proteins for a variety of compounds, like fatty acids, amino acids, bile salts, metals, hormones, drugs and pharmaceuticals, which has many physiological functions, such as maintaining the osmotic pressure and pH of blood and scavenging free radicals as an antioxidant 5 . It is an attractive macromolecular carrier, the lack of toxicity and immunogenicity make it an ideal candidate for drug delivery [6][7][8][9] . ...