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1 Chemical structure of GABA (γ-amino-butyric acid). GABA is a carboxylic

1 Chemical structure of GABA (γ-amino-butyric acid). GABA is a carboxylic

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Figure 1.1 Chemical structure of GABA (γ-amino-butyric acid). GABA is a...
Figure 1.4 Structure of a Cys-loop receptor. Above: Ribbon structure of...
Figure 1.8 Extracellular domain of a Cys-loop receptor. The...
Figure 1.10 Regions of rdl (the gene for the RDL subunit) which are...
+23 Figure 1.11 Distribution of RDL receptors in the adult house cricket...
Molecular pharmacology of an insect GABA receptor
Thesis
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  • Oct 2010
Cys-loop receptors are ligand-gated ion channels that are involved in fast synaptic neurotransmission in the central and peripheral nervous system. The Cys-loop receptor RDL (‘resistant to dieldrin’) is a GABA-gated chloride channel from Drosophila melanogaster and is a major target site for insecticides. The aim of this dissertation was to charact...
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