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Characteristics of the 288 patients with amyotrophic lateral sclerosis (ALS) included in the study, compared with the entire population of ALS patients during the study period in Stockholm,
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Background: Immune response changes have been reported in amyotrophic lateral sclerosis (ALS), but their clinical relevance remains undetermined. Therefore, we aim to evaluate the relationships between blood leukocyte subpopulations and prognosis of ALS.
Methods: A longitudinal cohort of 288 ALS patients with up to 5 years of follow-up during 2015-...
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Context 1
... final analysis cohort included 288 patients (68.6%), with at least one recorded differential leukocyte counts during the observation period. The included patients did not differ significantly in terms of demographic and clinical characteristics from the excluded patients (Table 1). About half of the patients had a single measurement of leukocytes whereas the other half had been sampled two or more times. ...Context 2
... . Table 3 Cross-sectional correlations between leukocyte populations and ALS functional rating scale-revised (ALSFRS-R) score and disease progression rate, a cohort study of 288 Table 1 Characteristics of the 92 patients with amyotrophic lateral sclerosis (ALS) included in the analysis of FlowC test, compared with the entire population of ALS patients during the study period 2 (2%) -*P value for the differences between patients included in the analysis and patients not included in the analysis; Wilcoxon rank sum test was used for the comparison of continuous variables whereas Chi-square test was used for the comparison of categorical variables. + Results available for 73 of the 92 patients included in the analysis, and 351 of the entire 420 patients in Stockholm. ...