Figure 2 - uploaded by Robert Feibel
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Ceremony at the Ether Dome of the Massachusetts General Hospital, 1960
Source publication
Henry R. Viets (1890–1969) was both a noted neurologist and medical historian. While at Harvard Medical School, from which he graduated in 1916, he attracted the attention of Harvey Cushing who directed Viets into these disciplines. Cushing arranged for Viets to take a fellowship in Oxford in the year after his graduation. With Cushing's recommenda...
Citations
... As a result, the increased ACh-induced activation of muscle AChRs increases muscle strength. These effects make it an important alternative drug for post-anesthesia residual muscle relaxation (non-depolarizing muscle relaxation) (Fuchs-Buder et al., 2023), myasthenia gravis (Feibel, 2021), acute colonic pseudo-obstruction (Adiamah et al., 2017), constipation (Kapoor, 2008), urinary retention (Cao et al., 2022), neurotoxic snake bites (Anil et al., 2010) and other conditions or diseases that cause muscular weakness due to dysfunction of the cholinergic muscle junction. ...
Neostigmine is a clinical cholinesterase inhibitor, that is, commonly used to enhance the function of the cholinergic neuromuscular junction. Recent studies have shown that neostigmine regulates the immune-inflammatory response through the cholinergic anti-inflammatory pathway, affecting perioperative neurocognitive function. This article reviews the relevant research evidence over the past 20 years, intending to provide new perspectives and strategies for the clinical application of neostigmine.
