FIGURE 3 - uploaded by Bargavi Purushothaman
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Cell migration (scratch assay) using MG-63 osteoblast like cells. For analyzing the healing property of the composites, cell migration assay was performed using MG-63 osteoblast like cells.
Source publication
Bioactive glass (BG) is a silicate based material, which is widely reported as a biocompatible system that is widely used in hard tissue regeneration. In the current study, to enhance the healing efficiency and in vitro bioactivity of 45S5 BG, alumina incorporated with 3 different concentrations (Al2O3-5%, 10% and 15%). Further structural propertie...
Citations
Wound healing research has revealed a plethora of data regarding various techniques for treating diverse types of wounds. It is well known that chronic wounds heal slowly and are vulnerable to infection. Also, there are numerous factors like destitute blood passage, undetermined inflammation, angiogenesis, neuropathy, and cell multiplication which overhang chronic wound healing. To eliminate the speculative features of chronic wounds, we made a consecutive survey on specific categories of biomaterials like bioglass, bioactive glass, bioceramics, biopolymers, and biocompatible metal oxide nanoparticles. In particular, the bioglass or bioactive glass which is a silica matrix composed of sodium, calcium, phosphorous, etc., is used for bone-bonding ability and easily dissolved in vivo conditions to repair damaged and wounded tissues with their peculiar physiochemical (surface area, porous nature, structural formation, mechanical stability) and biological properties (biocompatible, cytocompatible, osteoinductive, angiogenesis, hemostatic, antibacterial, and anti-inflammation). Furthermore, based on the existing literature studies, we summarized the healing of diabetes wound tendency by bioactive composite materials and offer detailed information on the method, techniques, and future technologies for wound healing.
