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Categories of serotonergic drugs
Source publication
Serotonin syndrome or serotonin toxicity is defined as an iatrogenic drug-induced toxidrome associated with increased intrasynaptic serotonin concentration in the central nervous system. Most cases are provoked by therapeutic doses of a combination of two or more serotonergic agents. The incidence of serotonin syndrome is on the rise, because of in...
Context in source publication
Context 1
... clinical practice, there are different categories of these drugs 1,2,3,4 . (Table 1) In this case, the patient was on selective serotonin reuptake inhibitors while being administered Meperidine and Ondansetron in the post operative period. Meperidine and 5 HT3 inhibitors impair serotonin reuptake from the synaptic cleft into the presynaptic neuron. ...Similar publications
Serotonin syndrome is a clinically diagnosed disorder that may occur secondary to medications that increase the release of endogenous serotonin, impair the reuptake of serotonin from the synaptic cleft, are direct serotonin receptor agonists, or increase the sensitivity of the postsynaptic serotonin receptor. In this case report, we describe the di...
