Cases of dengue fever (DF) and hemorrhagic dengue fever (HDF) according to epidemiological week 2009 and 2010 (Dirección General de Epidemiología). 

Cases of dengue fever (DF) and hemorrhagic dengue fever (HDF) according to epidemiological week 2009 and 2010 (Dirección General de Epidemiología). 

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Background. Dengue is a public health priority in Mexico. Since 2008, the dengue diagnostic algorithm for epidemiological and virological surveillance has been improved at InDRE and the public health laboratory network (RLESP) to optimize geographic representation, opportunity, sensitivity and specificity of the produced information. Methods. Dengu...

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... 2009, almost a quarter of a million probable cases were reported to the epidemiological surveillance system. In 2010 there were 127,840 probable cases, a decrease from the previ- ous year ( Figure 6). In the 2 years analyzed it was noted that the increase in cases from epidemiological week 31 decreased at week 45. ...

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... Another is that there is an increase in reporting of confirmed dengue cases, which has also been the case in areas such as the Americas from 2000 to 2010 (Guzman et al., 2013). The data identified 2009 and 2011 as epidemic years (Dick et al., 2012;Liao et al., 2015;Vázquez-Pichardo et al., 2011). Serotypes circulating in the years of 2009 and 2011 might have influenced these epidemics (Garcia-Rejon et al., 2011;Sanchez-Casas et al., 2013;VázquezPichardo et al., 2011). ...
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Accurately predicting vector-borne diseases, such as dengue fever, is essential for communities worldwide. Changes in environmental parameters such as precipitation, air temperature, and humidity are known to influence dengue fever dynamics. Furthermore, previous studies have shown how oceanographic variables, such as El Niño Southern Oscillation (ENSO)-related sea surface temperature from the Pacific Ocean, influences dengue fever in the Americas. However, literature is lacking on the use of regional-scale satellite-derived sea surface temperature (SST) to assess its relationship with dengue fever in coastal areas. Data on confirmed dengue cases, demographics, precipitation, and air temperature were collected. Incidence of weekly dengue cases was examined. Stepwise multiple regression analyses (AIC model selection) were used to assess which environmental variables best explained increased dengue incidence rates. SST, minimum air temperature, precipitation, and humidity substantially explained 42% of the observed variation (r² = 0.42). Infectious diseases are characterized by the influence of past cases on current cases and results show that previous dengue cases alone explained 89% of the variation. Ordinary least-squares analyses showed a positive trend of 0.20 ± 0.03 °C in SST from 2006–2015. An important element of this study is to help develop strategic recommendations for public health officials in Mexico by providing a simple early warning capability for dengue incidence.
... DENV serotype distribution. All four DENV serotypes have been shown to circulate in Mexico at different times ( Figure 4) [16,20,26], creating epidemic, endemic, and hyperendemic scenarios. According to a study by Falcón-Lezama et al., DENV-2 was the predominant serotype from 2000 until 2005, and DENV-1 became predominant in 2006 [16], although Rivera Osorio reported that DENV-3 was the most commonly isolated serotype in 2006 [32]. ...
... According to a study by Falcón-Lezama et al., DENV-2 was the predominant serotype from 2000 until 2005, and DENV-1 became predominant in 2006 [16], although Rivera Osorio reported that DENV-3 was the most commonly isolated serotype in 2006 [32]. Vázquez-Pichardo et al. reported serotype data gathered by Instituto de Diagnóstico y Referencia Epidemiológicos (InDRE) following the introduction of a new diagnostic algorithm with improved dengue serotype identification in 2008 [26]. Data for 2009 and 2010 show the continued predominance of DENV-1 (83% in both of these years), with DENV-2 representing most of the remaining cases (17% in 2009 and 16% in 2010). ...
... Data for 2009 and 2010 show the continued predominance of DENV-1 (83% in both of these years), with DENV-2 representing most of the remaining cases (17% in 2009 and 16% in 2010). The percentage of DENV-4 isolates was less than 1% in 2009 and 2010 [26]. For the period 1995-2003, Navarette-Espinosa et al. reported that 9% of isolates were DENV-1, 60% were DENV-2, and 31% were DENV-3 (there were no DENV-4 isolates) [33]. ...
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Background: Dengue manifestations can range from subclinical to fatal. The study of factors that influence dengue's clinical severity can provide information to potentially limit or predict severe cases. Secondary infection (SI) with a different dengue serotype has been recognized as an important determinant of severity. However, severe dengue (SD) manifestations, including shock, can happen during primary infection (PI) too and the mechanisms involved are less understood. To characterize the severe manifestations associated to PI, we distinguished between primary and secondary dengue cases in hospitalized patients from a region of low and recent dengue incidence in central Mexico. This region can serve as a model for dengue's behavior as it spreads to new areas worldwide. Methods: Dengue-specific immunoglobulin M (IgM) and IgG concentrations were measured in the serum of 78 hospitalized patients with dengue hemorrhagic fever, and their ratios were used to discriminate between PI and SI, as recommended by World Health Organization. Clinical and laboratory manifestations were compared between PI and SI. Results and Conclusions: PI was detected in 23% of hospitalized dengue cases, a proportion similar to that reported in high-incidence regions in Mexico. PI was more frequent in 16- to 40-year-olds, and was absent in patients older than 60 years. Only dengue with warning signs and SD were present in the studied population of hospitalized patients, and case frequency decreased with clinical severity both in PI and SI groups. No significant differences in demographics, laboratory tests, or symptoms were found between PI and SI, which illustrates that cases requiring hospitalization during outbreaks can be severe, even if they are PI. This information can help plan for sanitary contingencies in places where dengue is recently emergent and numerous PI cases are expected. The mechanisms involved in PI clinical severity need to be studied further.