CT of the paranasal sinuses showing expansion of the sphenoid bone demonstrating diffuse ground-glass matrix and sclerosis obliterating the sphenoid sinus cavity.

CT of the paranasal sinuses showing expansion of the sphenoid bone demonstrating diffuse ground-glass matrix and sclerosis obliterating the sphenoid sinus cavity.

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Fibrous dysplasia (FD) is an uncommon benign bone disorder of unknown etiology in which normal medullary bone is replaced by fibrotic and osseous tissue. FD of paranasal sinuses is usually secondary to extension from adjacent bones. It is rarely limited to the sinuses, let alone limited to the sphenoid sinus. Furthermore, the relationship between h...

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... and ibuprofen). She also complained of mild right nasal congestion and intermittent mild otalgia. Physical examination was normal apart from nasal septal deviation. Computed tomography (CT) of the paranasal sinuses showed expansion of the sphenoid bone demonstrating diffuse ground-glass matrix and sclerosis obliterating the sphenoid sinus cavity (Fig. 1). Magnetic resonance imaging (MRI) was highly suggestive of fibrous dysplasia of the sphenoid bone, which appeared as expanded mass with dark T2 signal and T1 hypointense signal (Figs 2 and 3). Near-total excisional biopsy was performed using endoscopic transeptal approach to sphenoid sinuses. Histopathological examination of several ...

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