2 CEUS scan of the right liver lobe showing a 21 × 20 mm thermal lesion obtained with two laser fibers

2 CEUS scan of the right liver lobe showing a 21 × 20 mm thermal lesion obtained with two laser fibers

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This chapter presents an overview of the most salient experimental data derived from studies on animal models or live animal organs that are the basis of the most relevant clinical studies performed in order to establish which were the most suitable physical parameters to kill cancer cells in a safe, selective, rapid, reproducible, predictable, rel...

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... Besides the objective size criteria, the presence of local pressure symptoms, progressive growth, and cosmetic concern may be considered as factors that strengthen the indication to LA. If suspected, retrosternal extension of large nodules should be evaluated with cross-sectional imaging, because a relevant immersion in the anterior mediastinum makes the ablation procedure technically cumbersome (13,32,42). ...
... When ultrasonographic features of the thyroid nodule are highly suspicious for benignity (e.g., spongiform and purely cystic nodules), the second fine-needle aspiration biopsy (FNAB) may be omitted. Cytologic assessment is not needed in hyperfunctioning nodules proved by scintigraphy (13,32,42). In cytologically benign nodules with suspicious US features, further clinical and cytological evaluation should be performed to rule out the risk of overlooking a malignant lesion. ...
... Mixed or predominantly cystic lesions are effectively treated with US-guided ethanol injection, a simple, safe, and inexpensive procedure. LA, however, may be performed immediately after fluid drainage in cystic nodules that recurred after ethanol injection (42). ...