Fig 1
Blasts showing typical cup-like nuclei (A) Typical blasts with cup-like nuclei (arrows), May-Grunwald Giemsa staining (×1000); (B) Blasts showing strong myeloperoxidase positivity, myeloperoxidase staining (×1000)
Source publication
In this study, we examined a cohort of Japanese patients with acute myeloid leukemia (AML) with cup-like nuclei. In particular, we attempted to provide a detailed definition of the clinical features of AML with cup-like nuclei. The clinical records of patients diagnosed with de novo AML were collected retrospectively. We showed that approximately 2...
Contexts in source publication
Context 1
... total, 13 patients diagnosed with de novo AML during the study period were included. Of these patients, 8 (61.5%) were men. Representative cup-like blasts are shown in Fig. 1A with marked myeloperoxidase positivity (Fig. 1B). MayGrunwald Giemsa bone marrow smears from case 1 demonstrate the cup-like nature of the nuclear invaginations in many of the blasts. The blasts were intermediate-sized with scant cytoplasm. Auer rods were not seen. Prominent nuclear invaginations were identified in > 10% of the blasts ...
Context 2
... total, 13 patients diagnosed with de novo AML during the study period were included. Of these patients, 8 (61.5%) were men. Representative cup-like blasts are shown in Fig. 1A with marked myeloperoxidase positivity (Fig. 1B). MayGrunwald Giemsa bone marrow smears from case 1 demonstrate the cup-like nature of the nuclear invaginations in many of the blasts. The blasts were intermediate-sized with scant cytoplasm. Auer rods were not seen. Prominent nuclear invaginations were identified in > 10% of the blasts in each patient. Overall, 3 patients (23%) were ...
