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Bellows pump design parameters and experiment design. a Bellows pump cross-section showing design parameters: radius R, amplitude α, height H, number of bellows N, and thickness T. b–e Variations of bellows cross-section
Source publication
A key challenge for microfluidics is efficient pumping of fluids, which typically requires equipment that is significantly larger than the pumped fluid volume. This paper presents a miniature elastomer bellows pumps that can be integrated with a microfluidic cartridge. The bellows pump features three-dimensional geometries enabled by additive manuf...
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Citations
Biosensing is vital for many areas like disease diagnosis, infectious disease prevention, and point-of-care monitoring. Microfluidics has been evidenced to be a powerful tool for biosensing via integrating biological detection processes into a palm-size chip. Based on the chip structure, microfluidics has two subdivision types: open microfluidics and closed microfluidics, whose operation methods would be diverse. In this review, we summarize fundamentals, liquid control methods, and applications of open and closed microfluidics separately, point out the bottlenecks, and propose potential directions of microfluidics-based biosensing.
