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Axial CT of a patient exhibiting distended gallbladder length of 10.5 cm (straight line), presence of pericholecystic fluid (arrow), hyperdense bile of attenuation 61HU (bullseye circle) and mucosal enhancement (arrowhead), features previously reported as associated with acute cholecystitis in the literature. Although acute gangrenous cholecystitis was eventually discovered at cholecystectomy and the gallbladder lumen had been distended with infected bile, no purulent material was aspirated

Axial CT of a patient exhibiting distended gallbladder length of 10.5 cm (straight line), presence of pericholecystic fluid (arrow), hyperdense bile of attenuation 61HU (bullseye circle) and mucosal enhancement (arrowhead), features previously reported as associated with acute cholecystitis in the literature. Although acute gangrenous cholecystitis was eventually discovered at cholecystectomy and the gallbladder lumen had been distended with infected bile, no purulent material was aspirated

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Objective Early detection of complicated cholecystitis, particularly gallbladder empyema, is important. Yet only a handful of patients are correctly diagnosed prior to intervention. The purpose of this study was to evaluate the sonographic and computed tomography features associated with gallbladder empyema compared with the intraoperative findings...

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... gallstone, hyperdense bile (> 20 HU), mucosal enhancement and pericholecystic fluid (Fig. 3). Some authors also reported additional findings including liver abscess and aerobilia, due to perforated gallbladder [6,14,17,18]. Our study found that none of the criteria above showed significant statistical association with gallbladder empyema (see Fig. 4). This is largely contributed by a smaller number of patients that had CT scan prior to intervention. Although not significant, we found that 87% of patients with thickened gallbladder walls developed gallbladder empyema. A similar pattern is also shown with mucosal enhancement (89%) and gallbladder distension (81%) of patients ...

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Gallbladder diseases are very common, and their diagnosis is based on clinical–laboratory evaluation and imaging techniques. Considering the different imaging diagnostic tools, ultrasound (US) has the advantage of high accuracy combined with easy availability. Therefore, when a gallbladder disease is suspected, US can readily assist the clinician in the medical office or the emergency department. The high performance of US in the diagnosis of gallbladder diseases is mainly related to its anatomic location. The most frequent gallbladder pathological condition is gallstones disease, easily diagnosed via US examination. Acute cholecystitis (AC), a possible complication of gallstone disease, can be readily recognized due to its specific sonographic features. Additionally, a number of benign, borderline or malignant gallbladder lesions may be detected via US evaluation. The combined use of standard B-mode US and additional sonographic techniques, such as contrast-enhanced ultrasonography (CEUS), may provide a more detailed study of gallbladder lesions. Multiparametric US (combination of multiple sonographic tools) can improve the diagnostic yield during gallbladder examination.