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The decision to postpone parenting has gained momentum in recent years, a shift driven by evolving social dynamics and improved access to fertility treatments. Despite their increasing prevalence, pregnancies at advanced maternal ages are associated with increased risks of adverse maternal and neonatal outcomes. This article addresses the associati...
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Objective: We aimed to investigate the association between maternal age and severe maternal morbidity (SMM) in a Korean population. Methods: Data for cases of delivery between 2003 and 2018 were extracted from the Korean National Health Insurance Service-National Delivery Cohort. The main outcome was SMM, which was determined using the Center for D...
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Background In frozen–thawed embryo transfer (FET) cycles, endometrial thickness (EMT) has been used routinely as the main clinical monitoring index. However, the current findings are conflicting. Method This was a single-center retrospective study of 2,054 couples (2,562 cycles) who underwent FET (including cleavage stage embryos and blastocysts)...
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Background: The number of women who delay pregnancy is increasing. Advanced Maternal Age/ AMA (pregnancies in women aged 35 years or older) have increased risks of complications, such as low birth weight/LBW (up to 1.59 times). The aim of this study is to know the association between AMA with LBW in primigravid births. Subjects and Method: This des...

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... OR odds ratio, CI confidence interval. www.nature.com/scientificreports/ to 33.4% in 2019 9 . During pregnancy, the diagnosis of TB is frequently delayed due to non-specific symptoms and their masking by pregnancy symptoms. ...
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Disparities exist between sexes regarding tuberculosis (TB) incidence, as well as disease severity and outcome. Using a nationwide TB registry database, we explored the impact of sex and age on extrapulmonary TB (EPTB) among all enrolled patients by (1) calculating the female proportion for every age category according to TB-affected locations, (2) calculating the proportions of EPTB stratified by sex according to age, (3) conducting multivariable analysis to examine the impact of sex and age on EPTB likelihood, and (4) assessing the odds of EPTB for female compared to male as reference in every age category. Further, we explored the impact of sex and age on disease severity among pulmonary TB (PTB) patients. Of all the TB patients, 40.1% were female, with a male-to-female ratio of 1.49. The proportion of females was lowest in their fifties, resembling a U-shape. The male-to-female ratios in PTB and EPTB were 1.67 and 1.03, respectively. Compared to men, women were significantly associated with EPTB in their forties, fifties, and sixties. Female patients with PTB had significantly lower odds of having cavitation and positive smear test results in their fifties. Significant differences were found concerning TB location and severity between sexes, especially during reproductive age.
... In Korea, the fertility rate is significantly declining. 22 The proportion of infants whose CPR incidence was highest decreased over the study years ( Figure 1) (Figure S2). When we adjusted for age and other confounding factors, the decreasing trend in CPR over time lost statistical significance (Table 3). ...
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Background Although the outcome of cardiopulmonary resuscitation (CPR) is still unsatisfactory, there are few studies about temporal trends of in‐hospital CPR incidence and mortality. We aimed to evaluate nationwide trends of in‐hospital CPR incidence and its associated risk factors and mortality in pediatric patients using a database of the Korean National Health Insurance between 2012 and 2018. Methods and Results We excluded neonates and neonatal intensive care unit admissions. Incidence of in‐hospital pediatric CPR was 0.58 per 1000 admissions (3165 CPR/5 429 471 admissions), and the associated mortality was 50.4%. Change in CPR incidence according to year was not significant in an adjusted analysis ( P =0.234). However, CPR mortality increased significantly by 6.6% every year in an adjusted analysis ( P <0.001). Hospitals supporting pediatric critical care showed 37.7% lower odds of CPR incidence ( P <0.001) and 27.5% lower odds of mortality compared with other hospitals in the adjusted analysis ( P <0.001), and they did not show an increase in mortality ( P for trend=0.882). Conclusions Temporal trends of in‐hospital CPR mortality worsened in Korea, and the trends differed according to subgroups. Study results highlight the need for ongoing evaluation of CPR trends and for further CPR outcome improvement among hospitalized children.