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... nodes were not palpable. Local examination revealed a diffuse swelling extending mentolabial sulcus, inferiorly below the lower border of mandible and antero-posteriorly extending from the midline to the level of corner of the mouth both side extending 1.5 cm size (Figure 1). Color over the surface appeared normal; no ulceration or discharge from the swelling was seen. ...
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... All these clinical and radiographic findings in our case were coincided with an aggressive form feature, which in agreement with many previous studies, especially Mezzour et al., 2017 (33) , Bonolis et al. 2017 (34) and Elitsa 2013 (35) who reported that an aggressive lesion is characterized by one or at least three of the above mentioned aggressive form features. The final diagnosis is based on its histopathological features, despite the clinical and radiological features are not pathognomonic (36) and often confused with other jaw lesions that pose challenge to oral diagnostician. (37) In our presented case, the provisional diagnosis was considered to be RC. ...
... The radiological appearance of the lesion cannot be considered as diagnostic for granuloma solely as it can be confused with many other lesions of jaw. Hence, the 9 ultimate diagnosis depends upon histopathology. Histologically giant cell granulomas show numerous multinucleated giant cells and mononuclear cells ( fi b r o b l a s t a n d h i s t i o c y t e -l i k e c e l l s a n d ...
Central giant cell granuloma (CGCG), also known as giant cell reparative granuloma, is a non-cancerous proliferative lesion of unknown etiology. It is a localized osteolytic lesion with the diverse biological behavior of aggression which most commonly affects the mandible and other jaw bones. It is a rare condition and its characteristic clinical or radiological features are still not well defined. It resembles to some neoplasms and can easily be misdiagnosed with Antro- Choanal Polyp, Angiofibroma, Squamous Cell Carcinoma and inverted Cell papilloma.We are reporting a case of rare presentation of CGCG arising from the maxillary sinus. This is a case report of a 15 year old boy who presented with the episodes of recurrent epistaxis and nasal obstruction. Diagnosis of giant cell granuloma was made on the basis of age presentation, rare location, and histological findings of excised specimen, which revealed central giant cell granuloma. This case helps to demonstrate the wide variation in the clinical and radiological features of CGCG and highlights the significance of histological features of this lesion.
