Antimicrobial sensitivity pattern of colistin resistant Gram-negative bacilli

Antimicrobial sensitivity pattern of colistin resistant Gram-negative bacilli

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Introduction and Aim: The increasing resistance in colistin is a major concern. The aim of the study was to compare the methods to identify the prevalence of colistin resistance and antibiotic susceptibility patterns of colistin resistant strains isolates from blood, urine and sputum samples at all ICUs including NICU and PICU and wards. Materials...

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Context 1
... percentage of antibiotic resistance pattern of all 16 bacterial isolates using Mikrolatest system is shown in [ Table 7]. High resistance rates to aminoglycosides, fluoroquinolones, penicillins, β-lactam/β-lactamase inhibitor combinations, cephalosporins, carbapenems and folate pathway inhibitors respectively were observed among all test isolates. ...
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... resistance rates to aminoglycosides, fluoroquinolones, penicillins, β-lactam/β-lactamase inhibitor combinations, cephalosporins, carbapenems and folate pathway inhibitors respectively were observed among all test isolates. Sensitivity of isolates to other drugs tested was shown in Table 7. Ampicillin / Clavulonic acid was sensitive in 2 and 14 were resistant, Piperacillin/Tazobactam was sensitive in 6 and 10 were resistant, Cefuroxime resistant was seen in all 16, Ceftriaxone was sensitive in 2 and 14 were resistant, Cefoperazone/Sulbactam was sensitive in 6 and 10 were resistant, Cefepime was sensitive in 1 and 15 were resistant, Imipenem was sensitive in 6 and 10 were resistant, Meropenem was sensitive in 4 and 12 were resistant, Amikacin was sensitive in 10 and 6 were resistant, Gentamicin was sensitive in 6 and 10 were resistant, Nalidixic Acid was sensitive in 10 and 6 were resistant, Ciprofloxacin was sensitive in 10 and 6 were resistant, Nitrofurantoin was sensitive in 10 and 6 were resistant, Colistin was resistant in all 16, Trimethoprim/Sulfamethoxazole was sensitive in 6 and 10 were resistant, and Tigecycline was sensitive in 4 and 12 were resistant (Table 7). ...
Context 3
... resistance rates to aminoglycosides, fluoroquinolones, penicillins, β-lactam/β-lactamase inhibitor combinations, cephalosporins, carbapenems and folate pathway inhibitors respectively were observed among all test isolates. Sensitivity of isolates to other drugs tested was shown in Table 7. Ampicillin / Clavulonic acid was sensitive in 2 and 14 were resistant, Piperacillin/Tazobactam was sensitive in 6 and 10 were resistant, Cefuroxime resistant was seen in all 16, Ceftriaxone was sensitive in 2 and 14 were resistant, Cefoperazone/Sulbactam was sensitive in 6 and 10 were resistant, Cefepime was sensitive in 1 and 15 were resistant, Imipenem was sensitive in 6 and 10 were resistant, Meropenem was sensitive in 4 and 12 were resistant, Amikacin was sensitive in 10 and 6 were resistant, Gentamicin was sensitive in 6 and 10 were resistant, Nalidixic Acid was sensitive in 10 and 6 were resistant, Ciprofloxacin was sensitive in 10 and 6 were resistant, Nitrofurantoin was sensitive in 10 and 6 were resistant, Colistin was resistant in all 16, Trimethoprim/Sulfamethoxazole was sensitive in 6 and 10 were resistant, and Tigecycline was sensitive in 4 and 12 were resistant (Table 7). The test results by BMD method by Mikrolatest MIC testi kit are summarized in Figure 1. ...

Citations

... On the contrary, a recent study by Hong et al. highlighted the fact that the colistin AST results obtained using the BD Phoenix system were comparable to those of the rBMD method [43]. The limited literature on the Mikrolatest kit suggests that it has relatively higher concordance rates with rBMD for in vitro colistin susceptibility [44,45]. ...