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Antidiabetic agents prescribed
Source publication
Background: Attainment of therapeutic goals in Type 2 Diabetes Mellitus (T2DM) necessitates the rational use of drugs, given the wide options available and the presence of co-morbid diseases. Objectives: To evaluate the drug utilization parameters and short-term outcome of pharmacotherapy in T2DM patients attending a tertiary hospital in Northern N...
Contexts in source publication
Context 1
... of Sulphonylureas and biguanides was the major line of therapy employed (53.27%) with Metformin/Glibenclamide dual therapy accounting for 42.7% of antidiabetic medications while 13.62% of the patient were on insulin preparations (Table 1). ...
Context 2
... was no statistically significant difference p>0.05 (Chi-square) in treatment outcome when patients that had an initial poor glycaemic control were compared with those with starting optimum glycaemic control (Figure 1) where Optimum glycaemic control level is (FBG 4.5-6.7 and 2hpp <10), Acceptable glycaemic control is (FBG 5- 8 and 2hpp >9) and Poor glycaemic control is (FBG >9 18 and 2hpp >10) . However, about 50% of patients who had poor glycaemic control at the beginning of the evaluation period had a satisfactory glycaemic control level at the end. ...
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Citations
... ional status of the organs of the elderly diabetics, the mean number of oral antidiabetic drugs per prescription was 1.6±0.42. It was an indication of rational prescription and it is better when compared to the result of a study obtained from Type 2 diabetic patients in northern Nigeria where the mean number of drugs per prescription was 5.2±0.098. [7] However, the mean for oral antidiabetic drugs in the prescriptions was not indicated. Another study by Bela et al in India reported the mean number of drugs prescribed as 7.8±2.5. [8] The mean FBS was 182mg/dl against the 80-110 ideal value. This was an indication of poor glycemic control and could be attributable to so many factors lik ...
Objectives
To describe antidiabetes medicines prescribing and utilization patterns and to demonstrate gender, and age specific differences in the antidiabetes medicines consumption in the National Health Insurance Scheme (NHIS).
Methods
One hundred and fifteen out-patients prescriptions that contained at least one antidiabetes medicine issued to different NHIS patients that attended the health facility in 2013 were used for this study. WHO drug prescribing indicators was used to evaluate the medicines prescribing patterns, while WHO Anatomical Therapeutic Chemical/Defined Daily Dose methodology was used to describe the antidiabetes medicines consumption patterns.
Results
The average number of all medicines prescribed per encounter was 5.9 ± 2.0. The percentage of medicines prescribed by generic names and antidiabetes medicines from NHIS essential medicine list were 53.2% and 49.0% respectively. Metformin alone and combinations were most predominantly prescribed, higher proportion of prescriptions comprised multi antidiabetes medicine regime (77.4%) than monotherapy (22.6%). Metformin alone, glibenclamide, and glimepiride made it to Drug utilization 90% segment with an index of adherence to the reference clinical guidelines of 83.6%. Metformin was the most consumed antidiabetes medicine and was equally consumed by both women and men (15.8 vs 15.9 DDD/1000 Patients/Day, p > 0.05). Compared to other age groups, patients aged 40–59 years consumed significantly higher metformin, glibenclamide, and glimepiride than other age groups (p < 0.05).
Conclusion
This study shows a tendency for irrational prescribing, metformin was the most prescribed and consumed antidiabetes medicine. No substantial gender difference was observed, but higher consumption of antidiabetes medicines was noted in patients aged 40–59 years than other age groups.
