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Anatomical, histological and ultrasound view of carotid artery segments and CIMT measurement. (Created with BioRender.com).
Source publication
Background
Segment-specific variations of carotid intima-media thickness (CIMT) have not been assessed in South Asian populations. The purpose of this study was to determine if segment-specific CIMTs or a composite-CIMT score is a better risk predictor of coronary heart disease in South Asian populations.
Methods
A comparative prospective study wa...
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Aim:
To examine the effects of 24-month treatment with ipragliflozin on carotid intima-media thickness (IMT) in type 2 diabetes patients.
Methods:
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Citations
... A previous study from Sri Lanka showed that composite CIMT was more predictive of CAD than segment-specific CIMT scores. [25] In our study, we found no significant difference in the mean CIMT of patients (0.65 ± 0.10 mm) and controls (0.62 ± 0.06 mm). A West Indian study reported that the mean CIMT in patients with ischemic stroke was 0.83 mm (SD: 0.14 mm). ...
... This study's results illustrated that compared to the CDT group, the CCO rate, mortality, thrombolysis time, thrombolytic agent dose, and length of hospital stay were significantly reduced in the PMT group; meanwhile, PMT had obvious advantages concerning postoperative fibrinogen levels and the runoff score. It is well known that lower runoff scores indicate improved blood flow in below-the-knee vessels, and a large number of studies have also confirmed that increased blood flow in below-the-knee vessels improves the long-term effect of lower-extremity arterial therapy [26,27]. ...
Objective:
The study aimed to investigate the safety and efficacy of the Solitaire™ AB Stent System (ev3 Inc., Plymouth, MN, USA) for the treatment of acute lower extremity ischemia (ALLI) compared with conventional catheter-directed thrombolytic therapy.
Methods:
Retrospective analysis of patients with ALLI treated in the Department of Interventional Radiology at the First Hospital of Nanjing from January 2017 to April 2020 divided into a conventional (CDT) group (n = 106) and a percutaneous mechanical thrombectomy (PMT) group (n = 55) according to the procedure. PMT was performed using the Solitaire™ AB stent system. The combined clinical outcomes of mortality, major amputation, recurrent ischemia, and major morbidity were compared between the two groups.
Results:
Of the 161 patients, 128 (79.5%) did not have a composite clinical outcome after 12 months of follow-up, namely, 78 CDT patients and 50 PMT patients, with significant differences in composite clinical outcome (26.4% vs. 9.1%, P = 0.010) and mortality (19.8% vs. 7.3%, P = 0.037) between them. Thrombolytic drug dose (19.34 ± 5.93 vs. 13.55 ± 6.54 mg, P < 0.001) and length of hospital stay (8.29 ± 3.91 vs. 5.49 ± 1.18 days, P = 0.003) were significantly lower in the PMT group.
Conclusion:
PMT with the Solitaire™ AB Stent System is safer and more effective in treating patients with Rutherford stage I-IIB ALLI, with the advantage of rapid opening of obstructed vessels, shorter thrombolysis time, reduced thrombolytic dose, and improved blood flow to the infrapopliteal vessels.
