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![An overview of the general stimuli for renin release, formation of angiotensin II (ANG II) via angiotensin I (ANG I) and the effects of ANG II. Haemorrhage stimulates renin release via all three mechanisms. Increased cerebrospinal fluid [Na + ] reduces renal sympathetic nerve activity (renal SNA) in sheep, while it may increase tubular flow and stimulate renal baroreceptors via increased arterial blood pressure. ANG II acts on the brain via parts of the brain that lack a functional blood-brain-barrier, circumventricular organs (CVOs). ACE, angiotensin converting enzyme.](profile/Robert-Frithiof/publication/242618702/figure/fig2/AS:650825361809408@1532180266898/An-overview-of-the-general-stimuli-for-renin-release-formation-of-angiotensin-II-ANG.png)
An overview of the general stimuli for renin release, formation of angiotensin II (ANG II) via angiotensin I (ANG I) and the effects of ANG II. Haemorrhage stimulates renin release via all three mechanisms. Increased cerebrospinal fluid [Na + ] reduces renal sympathetic nerve activity (renal SNA) in sheep, while it may increase tubular flow and stimulate renal baroreceptors via increased arterial blood pressure. ANG II acts on the brain via parts of the brain that lack a functional blood-brain-barrier, circumventricular organs (CVOs). ACE, angiotensin converting enzyme.
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