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Algorithm for determining the etiology of ascitic fluid. SAAG, serum-ascites albumin gradient. 

Algorithm for determining the etiology of ascitic fluid. SAAG, serum-ascites albumin gradient. 

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Article
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The purpose of this study was to provide evidence-based approaches to detect ascites, perform paracentesis, order tests, and interpret the results. A Medline search was performed to identify relevant articles. Of 731 identified articles, 50 articles were used. The most sensitive findings for ascites detection are ankle edema (93%), increased abdomi...

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Context 1
... fluid albumin determination is crucial in determining the etiology of the ascites. The serum-ascites albumin gradient (SAAG) has been shown to be superior to the exudate-transudate concept (using total ascitic fluid protein) for classifying ascitic fluid [9]. The SAAG is the absolute difference between the serum albumin and the ascitic albumin level. The SAAG has been shown to be directly related to an elevation of portal venous pressure [33]. Therefore, it is used to distinguish between sinusoidal portal hypertensive and non-portal hypertensive causes of ascites (Fig. 1). A high SAAG ( ≥ 1 g/dl) identifies ascites due to sinusoidal portal hypertension 97% of the time [9]. Once the cause has been established, it is not necessary to repeat the test for albumin in subsequent paracentesis unless clinically ...
Context 2
... ascitic total protein concentration is a reflection of the serum protein concentration and portal pressure [33]. Tra- ditionally, an ascitic fluid total protein level ≥ 2.5 g/dl was considered an exudate, while total protein < 2.5 g/dl was considered a transudate. This method was only 56% accu- rate in classifying the cause of ascites [9]. While it is not a useful test to distinguish between portal hypertensive and non-portal hypertensive causes of ascites, it is a useful ad- junctive test for elucidating the cause of ascites in the absence of portal hypertension (Fig. 1). A low ascitic total protein ( < 1.0 g/dl) has been associated with a higher risk of spontaneous bacterial peritonitis [35]. However, a consensus has not been reached on the routine use of prophylactic antibiotics to prevent SBP in this setting, as a main concern has been the selection of antibiotic-resistant organisms [1, 10]. High total protein levels ( > 1.0 g/dl) in ascitic fluid are commonly seen in secondary peritonitis (Table ...

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Citations

... The rate of immediate complications from ascites puncture is relatively low, making the procedure safe when performed according to current recommendations, and often compatible with outpatient management [1,2]. Minor complications, such as wall hematomas, occur in 1% of cases, and severe complications, such as hemoperitoneum or bowel perforation, occur in less than one case in 1000 [3]. ...
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Introduction Medical simulation has become an essential teaching method for all health professionals. It not only allows to acquire technical and non-technical knowledge, but also helps the maintenance of acquired knowledge in the medium and long term. Ascites puncture is part of the basic technical procedures learned by medical students during their internship. Objectives To evaluate the role of simulation-based learning of ascites puncture on the improvement of theoretical knowledge and maintenance of skills at 3 months. Methods We conducted an audit type study with two cycles of data collection at the simulation center at the Faculty of Medicine of Sousse between November 2020 and June 2021. We included learners in their third year of medical studies who had a hospital internship in the gastroenterology department at Sahloul Hospital in Sousse. All learners attended the initial simulation session on ascites fluid puncture. Thereafter, they were free to accept or refuse participation in the evaluation session that was scheduled after 3 months, depending on their availability. Results Forty learners participated in the procedural simulation of the ascites fluid puncture technique. Thirty-four (85%) were female and six (5%) were male. In our study, we showed that following procedural simulation training of ascites puncture, there was a significant improvement in the theoretical knowledge of the learners (p < 0.000). Objective assessment of technical skills after 3 months showed the benefit of performance maintenance (p < 0.000). Conclusion Our study confirmed the benefit of simulation-based learning on the improvement of theoretical knowledge and the maintenance of technical performance in the medium term.
... Apply negative pressure to the syringe during needle insertion until a loss of resistance is felt and a steady flow of ascitic fluid is obtained. After collecting sufficient fluid in the syringe for fluid analysis, either remove the needle and hold pressure to stop bleeding from the insertion site [11]. ...
... The rate of immediate complications from ascites puncture is relatively low, making the procedure safe when performed according to current recommendations, and often compatible with outpatient management (1,2). Minor complications, such as wall hematomas, occur in 1% of cases, and severe complications, such as hemoperitoneum or bowel perforation, occur in less than one case in 1000 (3). ...
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Introduction Medical simulation has become an essential teaching method for all health professionals. It not only allows to acquire technical and non-technical knowledge, but also help the maintenance of acquired knowledge in the medium and long term. Ascites puncture is part of the basic technical procedures learned by medical students during their internship. Objectives To evaluate the role of simulation-based learning of ascites puncture on the improvement of theoretical knowledge and maintenance of skills at 3 months. Methods We conducted a quasi-experimental study at the simulation center at the Faculty of Medicine of Sousse between November 2020 and June 2021. We included learners in their third year of medical studies who had a hospital internship in the gastroenterology department at Sahloul Hospital in Sousse. All learners attended the initial simulation session on ascites fluid puncture. Thereafter, they were free to accept or refuse participation in the evaluation session that was scheduled after 3 months, depending on their availability. Results Forty learners participated in the procedural simulation of the ascites fluid puncture technique. Thirty-four (85%) were female and six (5%) were male. In our study, we showed that following procedural simulation training of ascites puncture, there was a significant improvement in the theoretical knowledge of the learners (p < 0.000). Objective assessment of technical skills after 3 months showed the benefit on performance maintenance (p < 0.000). Conclusion Our study confirmed the benefit of simulation-based learning on the improvement of theoretical knowledge and the maintenance of technical performance in the medium term.
... [2] If the ascites is a transudate, 4-5 litres is usually the accepted upper limit of safe drainage to prevent large shifts of intravascular volume. [3] If the ascites is exudative, such as in our case or in TB peritonitis, all the fluid should be removed if possible. This is the second case of spontaneous Staphylococcal peritonitis to be reported. ...
... If the fluid is clear or straw coloured and free flowing, it is most likely a transudate, so no more than 5 L should be removed at a time. [3] If the fluid is cloudy, slow flowing, bloody, milky in appearance, further diagnostic studies are indicated and an attempt to drain all the ascites is appropriate. ...
... Catheter/needle insertion can be performed perpendicular to the skin or using a Z technique, in which the skin is gently pulled down before inserting the needle, creating a diagonal track between the skin and the peritoneal cavity. 156 Anecdotal reports have suggested that the Z-technique could minimize peritoneal fluid leakage after catheter removal 155,158 ; nevertheless, recent adult studies have failed to demonstrate a superiority of the Z-technique in terms of postprocedural fluid leakage. 159 In adults, repeated drainage of 4 to 6 L/day of ascitic fluid has become the standard of care. ...
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... Paracentesis is a common diagnostic and therapeutic procedure in the management of ascites, most commonly involving patients with liver disease or malignancy [16]. The procedure is typically very well tolerated, with a low prevalence of complications approaching 1%, particularly when performed with either direct ultrasound guidance (watching the needle under ultrasound for the entire procedure) or ultrasound assistance (use of ultrasound to pick a safe entry site) [17][18][19]. ...
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... Decompensated hepatic cirrhosis is the leading cause worldwide, and the ascitic fluid is usually transudate in nature with a serum-ascites albumin gradient (SAAG) >1.1 g/dl. [1][2][3][4][5] Ascites is the first sign of malignancy in around half of all patients with peritoneal carcinomatosis secondary to malignancies of the gynecological and gastrointestinal tracts. [6][7][8][9] Detection of malignant cells on effusion cytology in these patients is important for management and disease prognostication. ...
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... 6 Paracentesis is a safe procedure; however, possible complications include the following: Persistent leakage of asities fluid at the needle insertion site, abdominal wall hematoma, infection, perforation of surrounding vessels or viscera (extremely rare), Hypotension after large-volume fluid removal (more than 5-6 L) and subcutaneous edema due to leakage of ascetic fluid. [7][8][9] A pseudoaneurysm is a collection of blood formed outside a vessel, within the surrounding soft tissues. They are formed due to a connection or channel between blood collection and the damaged blood vessel. ...
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... A simple and low-cost bedside procedure like abdominal paracentesis may also be helpful in the diagnosis of malignancy-related ascites. Unfortunately, the sensitivity of ascitic fluid cytology for detecting malignancy is much lower at 57-67.1% and paracentesis does not provide core tissue [4][5][6][7][8]. Paracentesis is also not feasible in cases without ascites, which accounts for two-thirds of patients with peritoneal carcinomatosis [9]. ...
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... 9 Care should be taken to avoid far lateral sites, engorged veins or previous scars. 7 The landmarks can be shifted slightly laterally to account for scarring from regular paracentesis. We believe this approach to be safer and more anatomically correct in the absence of ultrasound guidance, and encourage a revision to Figure 4. ...