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Acacia nilotica (Linn), commonly known as “DesiKikar” is a tannin rich medicinal plant. It belong to
genus Acacia that contains 900 species. It has great Anti-viral and Cytotoxic potential. We have document
phytochemistry, ethnobotany, ethnopharmacological review of Acacia nilotica (Linn) and taxo-pharmacology of
genus acacia.
Citations
... Acacia nilotica is a tannin-rich medicinal plant, that belongs to the genus Acacia with about 900 species and has great anti-viral and cytotoxic effects (Raheel et al., 2014). The plant contains a significant quantity of terpenoids, alkaloids, polyphenols, saponins, proteins, and polypeptides (Ali et al., 2012;Kaur et al., 2005). ...
... Plantago ovata seeds (POS), Lallemantia royleana seeds (LR), Ocimum basilicum seeds (OB), Plantago ovata husk (POH) and Acacia nilotica gum (AN) were purchased from the local market of Lahore. (Aslam et al, 2014). Plant materials (seeds and gum) were purchased on Feb 3, 2022 and used on Feb 4, 2022 to March 27, 2022 for extraction of mucilage from seeds and to purify the gum. ...
A tablet is a compact dosage form that includes both the active pharmaceutical ingredient (API) and various excipients, where a binder acts as an excipient, imparting cohesive quality in the powdered material. The present study aimed to extract polysaccharides from plant samples; Plantago ovata seeds, Plantago ovata husk, Lallemantia royleana, Ocimum basilicum and Acacia nilotica and to investigate their efficacy as tablet excipients. The wet granulation method was adopted for tablet formulation. Three different formulations (3%, 5% and 7%) were prepared by varying the binder concentration (hemicellulose extracted from plant samples). The tablets were evaluated by pre-compression tests; Angle of repose, bulk density, tapped density, Carr's Index, Hausner's ratio and post-compression tests; weight variation test, friability test, disintegration test, thickness test and dissolution test. Results were compared with binder commercially used in paracetamol drug. All 5% and 7% formulations showed friability and hardness values within range. Results of all the formulations of disintegration time are within range except 7% Plantago ovata seeds and 7% Plantago ovata husk. All the extracted hemicellulose showed good binding potential but, in all respects, the best formulation was 7% Lallemantia royleana, which has the potential to replace the synthetic binders in the pharmaceutical industry.
... Acacia nilotica L. (Raheel et al., 2014; Jamila and Rahman, 2016) commonly known as Babla in Bangladesh belonging to the family of Fabaceae (Raheel et al., 2014;Rahmatullah et al., 2009) is a commonly growing medium sized tree. Acacia nilotica popularly regarded as a medicinal plant in the South East Asian region (Muniraet al., 2013). ...
... Acacia nilotica L. (Raheel et al., 2014; Jamila and Rahman, 2016) commonly known as Babla in Bangladesh belonging to the family of Fabaceae (Raheel et al., 2014;Rahmatullah et al., 2009) is a commonly growing medium sized tree. Acacia nilotica popularly regarded as a medicinal plant in the South East Asian region (Muniraet al., 2013). ...
Aqueous extraction from fresh leaves of Acacia nilotica by Ultrasound Assisted Extraction (UAE)method was proposed in the present study. The intended method was occupying most of the features of the green extraction method. Efficiency and efficacy of the proposed extraction method was compared with the conventional extraction method and found satisfactory performance. The % yield (extraction efficiency) of the proposed method was observed higher than the conventional methanol and ethanol extraction. Similarly presences of tested phytochemicals were also higher than the conventional method. Antimicrobial study (extraction efficacy) was performed against S. aureus(Gram +ve) and S. dysenteriae (Gram-ve) bacteria and found almost similar antimicrobial activities with the conventional crude extract. Based on the experiment the Aqueous UAE method may be standardized as an effective green extraction procedure.
... The phytochemical studies showed that A. niloctica contains tannins, terpenoids, crude protein kaempferol, alkaloids, phenols, volatile oil, essential oil, steroids, oleosins, terpenes, resins saponins, steroids, triterpenoids, and flavonoids. [90] Its pod was reported to contain tannins and polyphenolic compounds. [90] Aqueous and ethanol extracts of A. nilotica stem bark were said to possess antimicrobial activity, suppress HIV-1 replication and hepatitis C virus. ...
... [90] Its pod was reported to contain tannins and polyphenolic compounds. [90] Aqueous and ethanol extracts of A. nilotica stem bark were said to possess antimicrobial activity, suppress HIV-1 replication and hepatitis C virus. [91,92] Moreover, methanolic extracts of its seeds showed anti-HSV type 1 and 2 activity . ...
In the current century, the development of medicine and molecular biotechnology led to successful containment and even eradication of some human pathogens, especially in developed countries. However, some pathogens have evolved, resulting in the emergence of other infectious diseases in developed countries. Human socioeconomic activities and the advancement of technology and transportation have led to the quick movement of humans to different parts of the world. There is a significant concern that this movement enhances the distribution of pathogens, making it difficult to contain, as witnessed with the global spread of the 2009 influenza pandemic within only 3 months and the 2014 Ebola outbreak, which spread in various West African countries within 8 months. Natural products obtained from plant sources can be identified as the next-generation antibacterial and antiviral alternatives. In developed countries, 80% of the population depends on traditional medicine for their primary healthcare issues, according to the World Health Organization (WHO). Relatedly, India is one of the highest producing countries for medicinal herbs. It is considered an international botanical garden. Therefore, the focus of this current review was on the importance of using plants to treat bacterial and viral diseases due to the many advantages of these plants.
... cm. Flower is mostly golden yellow in color and covered by globules heads and having a diameter is about 1.2-1.5 cm, which are to be found at the end of the branches [11]. There is construction between seeds and pods which looks like necklace. ...
Ancient civilizations were mostly relied on the natural flora and fauna for fulfillment of their basic needs such as food, shelter, clothing, transportation and the medicines. According to the WHO, approximately 21,000 plants were used for medicinal purpose across the world. Among the well-known medicinal plants, Acacia nilotica (L.) Delile (family Fabaceae) is an imperative medicinal plant of subtropical and tropical regions, locally called Babul/Kikar in India. The different plant parts secrete different phytochemicals constituent and theses constituents used to treat various diseases. This study was performed to provide the information concerning phytochemical and crystalline properties of this important medicinal plant. These findings would be helpful to use this plant more as natural source for development of novel herbal drugs to cure many diseases.
... Conventionally, it is used to treat leukoderma, gonorrhea, diarrhea, paralysis, eye pain, and tooth and gum diseases. [4] Psidium guajava or Guava popularly known as "poor man's apple of the tropics"; belongs to the Myrtaceae family. The plant is considered to be originated in tropical South America and is widely grown in tropical areas such as India, Bangladesh, and West Indies. ...
Introduction: In this study, extracts of Acacia nilotica, Elettaria cardamomum, Psidium guajava, and Glycyrrhiza glabra were prepared using supercritical fluid extraction (SFE) at different pressures and 50°C constant temperature. The antimicrobial activities of extracts were evaluated against oral pathogens, namely, Enterococcus faecalis, Streptococcus mutans, Staphylococcus aureus, and Candida albicans. Materials and Methods: The antimicrobial activities of extracts were evaluated against oral pathogens using agar well diffusion method. Phytochemical analysis of A. nilotica twig was done using gas chromatography-mass spectrometry (GCMS). Statistical analyses of data were performed by one-way ANOVA using MS-Excel and principal component analysis was performed using statistical software XLSTAT 2018. Results: All plants extracts exhibited significant activity at P < 0.05 with inhibitory zones ranging from 8 to 42 mm and minimum inhibitory concentration (MIC) values from 0.19 to 3.12 mg/ml. A. nilotica twig extract obtained at 400 bar pressure showed the highest zone of inhibition (42.07 mm) and lowest MIC (190 µg/mL). E. cardamomum and G. glabra extracts showed moderate activity while P. guajava extracts showed least activity against the oral pathogens. GC-MS analysis of A. nilotica twig confirm the presence of functional moieties of stigmasterol, clionasterol, betulinaldehyde, eugenol, α-terpinyl acetate, and 22,23-dihydrobrassicasterol in the extract which could be responsible for its antimicrobial efficacy and may prove beneficial in oral care products. Conclusion: The extraction of antimicrobial agents from plant materials using SFE at low temperatures avoids the thermal degradation and use of toxic solvents. A. nilotica twig at 50°C and 400 bar showed the significant antimicrobial potential, hence it can be processed to obtain effective and cheaper drug due to higher biomass availability. Chemical profiling of SFE extract by GC-MS analysis proved helpful in the identification of compounds. Furthermore, bioactive compounds should be explicated for their exact mechanism of action with the target pathogens.
... A. nilotica is commonly known as Babul/Desi-kikar. Traditionally the bark, leaves, aerial part and flower of this plant is used in Raigarh district of Chhattisgarh for the treatment of congestion, diarrhoea, haemorrhoids, dysentery, cancers and/or tumours, fever, tuberculosis, ophthalmia, leprosy and menstrual problems [13,27]. Administration of the methanolic extract of A. nilotica in rat results in the restoration of the increased serum enzyme level of ALT, AST, and ALP due to the acetaminophen-induced liver damage to normal range level. ...
Jaundice is one of the most common medical condition affecting infants, children, and adults. Jaundice is not a disease but it is a visible sign and symptom of liver disease which occurs when there is an increase in the amount of bilirubin circulating in the blood due to the abnormal metabolism and excretion in the urine. Medicinal plants are being used long ago by our ancestors for the treatment of jaundice. At the present era, consumption of these herbal medicines is increasing at a high speed, due to its less or no side effect and cost-effectiveness as compared to synthetic medicines. This review describes approximately 55 medicinal plants which are used by rural and tribal people of different area of Chhattisgarh for curing jaundice. The data was collected from different kinds of literature survey from the year 1993 to 2018. This review has been conferred in a systematic way which includes plant's vernacular name, botanical name along with its family, part used and ethnomedicinal uses in a tabulated form and also the description of scientific evidence behind the folklore uses of some medicinal plants along with their mechanism of action which have been reported in different kinds of literature. The current study may be useful for the development of new medicines for the treatment of jaundice.
Traditional preparations of medicinal plants with antimicrobial activities have been extensively used in the West African regions. This study was carried out to identify the antimicrobial properties and synergistic effects of the bioactive compounds of selected medicinal plants against diarrhoea causing pathogens. Using cold maceration methods, extracts from Vernonia amygdalina (22.86g), Acacia nilotica (22.80g), Anogeissus leiocarpus (22.87g), Carica papaya (19.05g),, Piliostigma thoningi (22.80g), and Khaya senegalensis (13.94g).The highest extract yield was obtained in A. leiocarpus The plant crude extracts exhibited varying degree of antibacterial activities at various concentrations against Vibrio cholerae, Klebsiella pneumoniae and Salmonella enterica serovar, with A. leiocarpus (32.33±0.73, 34.00±1.15f, 36.33±1.17)and K. senegalensis (36.00±0.81f, 19.00±0.98, 22.00±0.69) having the highest antibacterial activity as they showed significantly higher zones of inhibition at all concentrations against all the test organisms. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) was observed and recorded at 1.02±0.12, 1.04±0.29 and 1.92±0.23 mg/mL concentrations. The most active extracts were fractioned by column chromatography and, n-Hexane fraction of the most active crude extracts A. leiocarpus (0.64g) and K. senegalensis (0.46g) produced the highest yields followed by the aqueous and ethyl acetate fractions. Significant difference was observed in the antibacterial activity of A. leiocarpus and K. senegalensis fractions. All fractions of A. leiocarpus (aqueous, and n-Hexane) fractions had higher activity against all test organisms (36.67±1.00, 32.00±0.23 and 31.00±1.56) while Ethyl acetate fraction of K. senegalensis showed activity against K. pneumoniae and V. cholerae while no activity against S. enterica serovar Kentucky. The synergistic effect of column chromatography fractions of A. leiocarpus and K. Senegalensis was concentration dependent as one of inhibition increase with increasing concentration of the fractions. However, there was no significant difference between all experimental animals from all groups when compared to the control. Significant difference was observed in some liver parameters including a decrease in Alanine amino transferasae (ALT) and aspartate amino transferasease (AST) and increase in Total protein and albumin values. Significant differences were also observed in lipid parameters, kidney function and haematological parameters. Histological analysis of the liver and kidney of infected mice administered with A. leiocarpus and K. senegalensis fractions showed largely preserved architecture signifying that the plant extracts did not cause any detrimental changes and had no toxic effect. Therefore, the plant crude and fractions are recommended for the treatment of diseases caused by the test organism based on traditional medicine rules and regulations.
ABSTRACT
Ethno-botany accounts for the study of relationship between people and plants for their use as medicines, food, shelter, clothing, fuel, fodder and other household purposes. India is a repository of
medicinal plants. Different medicinal plant parts and their products have been used in traditional medicine since time immemorial. They still play an important role in effective disease control with no
side effect and have natural origin. They are considered as the great source of unique compounds for the development of medicines for the cure of various diseases. The present article is an attempt to
explore and comprehensively highlight the biological activities, pharmacological actions and medicinal applications of three plants namely Acacia nilotica, Albizia saman, Azadirachta indica.
