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Context 1
... determine the optimum wavelength for the assay, the UV spectra of MET and CGN were investigated, MET and CGN were found to exhibit λ max at 232 and 227 nm, respectively, as shown in Figure 2, UV detection at 227 nm was selected as the most suitable wavelength to obtain the highest possible sensitivity for the impurity CGN with adequate sensitivity for MET. ...
Context 2
... determine the optimum wavelength for the assay, the UV spectra of MET and CGN were investigated, MET and CGN were found to exhibit λ max at 232 and 227 nm, respectively, as shown in Figure 2, UV detection at 227 nm was selected as the most suitable wavelength to obtain the highest possible sensitivity for the impurity CGN with adequate sensitivity for MET. ...
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Citations
... CYG is considered as skin irritant, mutagenic and carcinogenic substance [23,24]. Different chromatographic approaches for the estimation of metformin in the existence of cyanoguanidine or with linagliptin have been documented [24][25][26][27][28][29][30][31]. Many published articles confirmed the solubility of proposed compounds in methanol [8,24,29]. ...
