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A schematic diagram of the eukaryotic cell cycle is presented. The respective phases of the eukaryotic cell cycle are indicated: mitosis (M), gap 1 (G1), synthesis (S) and gap 2 (G2). The relative amount of time spent by a typical eukaryotic cell in each phase is roughly equal to the depicted lengths of the respective phases. The hatched arrow represents the direction of the cycle. The individual stages of mitosis are listed to the right in temporal order. Respective cellular events of each mitotic stage and cytokinesis are depicted in the highly schematic model of a dividing cell. Only select events relevant to this discussion are shown and events/structures depicted may span more stages than indicated. See text for relevant references and discussion. PM= plasma membrane; NE= nuclear envelope; MS= mitotic spindle; SC= sister chromatids (separated chromosomes are also indicated); MT= microtubules. Disassembling (prometaphase) and reassembling (telophase) NEs are indicated by hatch marks

A schematic diagram of the eukaryotic cell cycle is presented. The respective phases of the eukaryotic cell cycle are indicated: mitosis (M), gap 1 (G1), synthesis (S) and gap 2 (G2). The relative amount of time spent by a typical eukaryotic cell in each phase is roughly equal to the depicted lengths of the respective phases. The hatched arrow represents the direction of the cycle. The individual stages of mitosis are listed to the right in temporal order. Respective cellular events of each mitotic stage and cytokinesis are depicted in the highly schematic model of a dividing cell. Only select events relevant to this discussion are shown and events/structures depicted may span more stages than indicated. See text for relevant references and discussion. PM= plasma membrane; NE= nuclear envelope; MS= mitotic spindle; SC= sister chromatids (separated chromosomes are also indicated); MT= microtubules. Disassembling (prometaphase) and reassembling (telophase) NEs are indicated by hatch marks

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The Role of Proteins and Lipids in Organelle Biogenesis in the Secretory Pathway
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  • Jun 2007
Membrane compartments in the secretory pathway retain their identity in spite of continuous membrane and protein flux through each compartment. A challenge in cell biology is to discover how compartment identity is established and maintained. A related issue is how protein and membrane cargo is sorted from resident molecules in a donor compartment...
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