A myxoid liposarcoma of the breast in a 44-year-old woman with a history of phyllodes tumor. A. A phyllodes tumor was confirmed 7 years ago. Gray-scale US shows a 3.6-cm oval, well-circumscribed, isoechoic mass in the left breast at the 11 o'clock position. Doppler imaging shows increased internal and rim vascularity in the mass.

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... of the left breast for borderline phyllodes tumors seven years earlier. An iU22 scanner (Philips Healthcare, Andover, MA, USA) was used for US which revealed a 3.6-cm oval, well-circumscribed, isoechoic mass in the left breast at the 11-o'clock position. Doppler US imaging revealed increased internal vascularity as well as vessels in the rim (Fig. ...

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... this visit, a 6.2 cm × 5.8 cm oval and an equal-to-high density mass in the left upper central to upper outer quadrant of the breast, unobscured by overlying breast parenchyma and free of microcalcifications, were observed in standard mammography (Fig. 1B). An ML6-15 linear transducer (LOGIQE10 scanner; GE Healthcare, Waukesha, WI, USA) was used to perform a breast US, in which a 5.0-cm oval, well-circumscribed solid mass was observed in the left breast at the 12-o'clock position, adjacent to a previous excision scar. The mass was heterogeneous, with multiple faint echogenic lines. It ...

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... in with the echogenic lines. There were no clefts, which are common radiologic features of cystic spaces with slit-like patterns. Color Doppler US imaging revealed mild peripheral vascularity. The mass was compressible and soft. Shearwave elastography revealed homogeneous dark blue in color, with elasticity values ranging between 0 and 36 kPa (Fig. 1C). No suspicious lymph nodes were observed in the left ...

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... on T2-weighted images. The first post-contrast acquisition and four repeated post-contrast images were acquired at 90-and 60-second intervals, respectively. In the early phase (90 seconds after the enhancement), they found heterogeneous peripheral enhancement and a type I persistent enhancement pattern on the time-signal intensity curve ( Fig. 1D). . A myxoid liposarcoma of the breast in a 44-year-old woman with a history of phyllodes tumor. B. Upon this visit, craniocaudal and mediolateral oblique mammogram shows a 6.2 cm × 5.8 cm, oval, and equal-to-high density circumscribed mass on the left upper central to upper outer breast. C. Gray-scale US shows a 5-cm oval and ...

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... encapsulated (7.5 cm × 7.0 cm × 5.0 cm in size). The cut surface showed a grayish, gelatinous mass. Microscopic examination revealed abundant myxoid stroma with a striking plexiform, delicate, and arborizing capillary network. The tumor showed patternless arrays of uniformly small and ovoid cells, without morphological adipocyte differentiation (Fig. 1E). The final pathological diagnosis was a low-grade myxoid liposarcoma of the ...