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A list of all RNA viruses with their structure and tentative role of BioActive Compounds present in sweet Lime. 15-21 22-29
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Sweet lime (Citrus limetta), known as ’Mousambi’ or ’Mosambi’ in India, is one of the best citrus fruits regarding its nutrient contents. Its bioactive compounds (BAC) are exclusively used for multiple clinical applications considering many therapeutic benefits not only in Asian countries but also in the western world. The fruit pulp and juice are...
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Dengue virus (DENV) is an enveloped, single-stranded RNA virus, a member of the Flaviviridae family (which causes Dengue fever), and an arthropod-transmitted human viral infection. Bangladesh is well known for having some of Asia’s most vulnerable Dengue outbreaks, with climate change, its location, and it’s dense population serving as the main con...
Citations
... Citrus fruits were well known for their healing qualities and were utilized to address a range of illnesses, including gout, scurvy, digestive problems, and skin diseases [34]. They were also employed as an antidote to poison and as an antiseptic during the plague. ...
The synthesis of the nanomaterial is crucial for its characteristics, as well as physiological features. Green nanoparticle production, which reduces metal ions using natural extracts rather than industrial chemical agents, has been created to lower costs, minimize pollution, and improve environmental and human health safety. An aqueous and methanolic extract of a combination of Citrus sinensis and Citrus limetta peel was utilized for the green synthesis of cobalt nanoparticles. UV–Visible, Fourier-transform Infrared, X-ray diffraction (XRD), scanning of electron microscopy (SEM) and other techniques were employed to describe the prepared cobalt nanoparticles. The crystal structure of cobalt nanoparticles was revealed by XRD study. The SEM images of the cobalt nanoparticles revealed the usual subdivision dimensions of 20–30 nm. Using the well diffusion method, the antibacterial activity of the crude extract derived from the combination of the two plants mentioned above and the biosynthesized cobalt nanoparticles was assessed. The result showed that the crude extract and cobalt nanoparticles exhibited antibacterial activity and cobalt nanoparticles exhibited much higher activity than the crude extract. Overall, these findings revealed that formulated cobalt nanoparticle treatment considerably prevented the development of different micro-organisms.
... 21,22 Sweet lime juice benefits dengue patients due to its bioactive compounds, including ascorbic acid, B vitamins, amino acids, and polyphenols. 23 In the present study, vitamin D was statistically significant. Vitamin D regulates calcium and phosphorous metabolism, is crucial for bone development, and acts as an immunomodulator, targeting immune cells, thereby increasing the risk of immune system issues and infection amelioration. ...
Purpose: Dengue is one of the common public health issues globally where laboratory diagnostic test values of patients are primarily focused on hematological parameters. Micronutrients equally take a role in quick recovery, and active cum passive immunity is not mainly considered during and post-recovery of patients.
Materials and Methods: A cross-sectional study with a purposive sampling method was applied using pre-tested close-ended questionnaires and laboratory data (soft copies/hard copies) of participants admitted to hospitals or nursing homes within the North -24 Paraganas district from November 2021 to October 2022. 110 male and female patients of 40-60 years reported dengue fever (non-hospitalized cases), and dengue hemorrhagic fever (hospitalized cases) was considered based on 15 variables. STATA version 18.0 software analyzed data using multivariate regression and range plots.
The Cronbach’s alpha value was 0.72, and the consolidated probability value shows 0.01 (p<0.05), which denotes that the multivariate model was statistically significant and was rightly decided to include the relevant independent variables. Calcium, vitamin D, and total protein were statistically significant as P values were 0.01, the same for each. Similarly, p=0.05 was the same for Total Leukocyte count (TLC) and Alkaline phosphatase (ALP).
The study concludes that micronutrients like calcium, protein, vitamin D, etc., are often considered secondary recommendations in dengue treatment. A balanced, nutrient-rich diet for dengue patients is needed to maintain sustained immunity by extensively monitoring calcium, vitamin D, and total protein intake during and after recovery.
... A variety of secondary metabolites are present in citrus fruits. Ascorbic acid and secondary metabolites such as phenolic acid, coumarins, carotenoids, flavonoids, alkaloids, and limonoids are best found in citrus fruits ( Banerjee & Pal, 2021 ). These bioactivities, which include antioxidative, anti-inflammatory, and anti-cancer properties, as well as cardiovascular and neuroprotective effects, are crucial for maintaining human health. ...
... This study found 86% moisture, 11.72 g of carbohydrates, 0.58 g of protein, and 1.23 g of dietary fiber in pineapple. Another report determined that mosambi contained 5.20 g of carbohydrates, 0.21 g of fat, protein of 0.77 g, and fiber of 2.07 g [32]. In the present study, it was determined that it contained approximately 4.80 g of carbohydrates, 0.21 g of fat, 0.77 g of protein, and 2.70 g of crude fiber per 100 g of fresh fruit. ...
Objectives
The aim of this study was to evaluate the effect of fruit juices on Multi-Drug Resistant (MDR) bacterial pathogens involved in Urinary Tract Infections (UTIs) and Sexually Transmitted Infections (STIs) among tribal women in the district Anuppur, Madhya Pradesh, India.
Methods
Fresh juices of lemon (Citrus limon), amla/Indian gooseberry (Phyllanthus emblica), pineapple (Ananas comosus), mosambi/sweet lime (Citrus limetta), orange (Citrus sinensis), kiwi (Actinidia deliciosa), and pomegranate (Punica granatum) fruits were evaluated for in vitro antibacterial activity against bacterial pathogens involved in UITs and STIs among tribal women. Physico-chemical analysis of fresh fruits was also carried out by measuring the pH, moisture, protein, fat, crude fibre, carbohydrate, and ascorbic acid content.
Results
Lemon and amla juice showed better antibacterial activity against the pathogens as compared to other juices. MIC results fruit juices against UTIs and STIs pathogens vary depending on the specific pathogen and juice chemical constituents. The physico-chemical analysis showed that the moisture content was highest in mosambi (90%), followed by orange (87%). Ascorbic acid content was found highest in amla (540 mg/100 g), followed by kiwi (90.3 mg/100 g). Pomegranate showed highest concentration of carbohydrate (15.28 g/100 g), fat (1.28 g/100 g), and protein (1.65 g/100 g). Lemon juice had lowest pH of 2.20, followed by amla 2.67.
Conclusion
The lemon juice showed highest antibacterial activity against MDR bacterial pathogens involved in UTIs and STIs among tribal women in district Anuppur, Madhya Pradesh, India. The low pH of lemon may be responsible for its high antibacterial activity as compared to other juices.
... The fruit contains polyphenols, including flavanones, hesperetin, naringenin, and chlorogenic acid. 10 According to the study, weight management should be a significant factor or comorbidity for dengue, mainly severe. As per the study, children and adolescents with severe plasma leakage (DHF grades III and IV) were more likely to be overweight than patients with mild plasma leakage (DHF grades I and II) (45.5% vs. 18.8%). ...
Dengue fever has become one of the most significant public health issues in tropical and subtropical countries, including India. Most of the states in India report dengue fever cases during and after the moon soon each year. The affected patients have been at their homes for 4-5 days, either from fever or acute signs of dehydration, low platelets, vomiting, abdominal pain, and fever. Some of these seriously ill patients are admitted to the hospital for IV fluids, hydration, and monitoring of their vital signs. Overall, this brief review is based on data from the World Health Organization, the National Center for Vector Borne Disease Control (NCVBDC, govt. of India), and other relevant portals searched by relevant keywords. This paper’s primary goal is to present and review home-based, low-cost nutrition integrated care for dengue After reviewing the data, the study showed the recent three years of dengue status in all the states of India.Using a mosquito net, paracetamol as a fever-reducing drug, and the best food through a maximum liquid diet are already proven preventive measures against infectionsIn addition to extra water cum electrolyte drinks, all macro and micronutrients are essential proportionally for managing platelet count and boosting immunity against the virus. Sufficient and complete data is needed to do more research in community health and therapeutic nutrition.
As accumulating evidence ties dietary ingredients to disease therapy and prevention, the notion that food can be nutritionally beneficial and health-promoting is gaining favour in the public sphere and among the scientific community. The most popular fruit after mangoes, tomatoes, and bananas, citrus fruits represent one of the most important and beneficial plant products. Citrus fruits (oranges, lemons, mandarins, limes, tangarines etc.) are a high source of vitamins, minerals, dietary fibres, pectins etc. They also comprise active phytochemicals like phenolic acids, flavones, flavanones, and flavonols, which are widely thought to protect our health due to their significant biomedical potency. These include massive antioxidant, antimicrobial, antiatherogenic, antitumor, anti-inflammatory, anticlotting efficacy, etc. Numerous research investigations have found a beneficial relationship between phytochemical-rich meals (particularly flavonoid-rich foods) and a reduction in a variety of significant health complications. The efficacy of citrus fruit extract is backed up by robust indications from both types of studies (ex vitro and ex vivo) that have provided insight into the fundamental mechanisms at work. Citrus fruit extracts are excellent candidates for nutraceuticals and functional foods aimed at managing microbial infection, diabetes, cardiovascular disease, cancer, and other major health concerns. Excessive reactive oxygen radical production during viral infection, inflammation, and other pathogenic conditions results in substantial cell damage, as found most prominently in the COVID-19 consequence. Various studies are also in good agreement that hesperdin, vitamin C, dietary fibers, etc. found in citrus fruits have the potential to mitigate those pathologic impacts associated with COVID-19. Citrus fruits are incredibly rich in vital substances that may influence immunity and protect cellular organisms or the environment from massive oxidative stress, along with other potential health benefits. Additionally, a wide range of citrus fruit associated byproducts and food waste include significant levels of bioactive compounds having possibilities for use in animal health care, feed, and processed foods. This chapter discuss about how the bioactive phytocomponents of different citrus fruits can be used to treat diseases and keep people healthy.
Corrosion occurs as a result of acid-based cleaning process in petroleum industry. Some of the procedures require 15% hydrochloric acid (HCl) solution thus speeding the corrosion rate. In this study, Citrus limetta pulp waste was used to obtain corrosion inhibitor for stainless steel (SS)-410 in presence of 15% HCl solution. The C. limetta pulp waste extract has shown maximum 90.90% corrosion inhibition efficiency at 4 g/L in 15% HCl solution using potentiodynamic polarization analysis. Scanning electron microscopy, atomic force microscopy and X-rays diffraction study confirmed the adsorption of the pulp waste extract on the SS surface. The pulp waste extract followed Langmuir adsorption isotherm thus confirming monolayer formation on the surface of SS-410. Theoretical and computational studies confirmed that Linalool was main phytochemical responsible for anti-corrosive effect. Linalool and SS-410 surface interactions was studied using molecular simulation. Overall, C. limetta pulp waste extract has shown anti-corrosive behaviour in 15% hydrochloric acid on SS-410 surface.
Abstract:
Citrus fruit has great importance all around the world. Many citrus species are cultivated in Asian subcontinent. Among them, Sweet lime (Citrus limetta) also known as “mosambi”are harvested in the Indian subcontinent. Herbal drugs are considered to be the oldest remedy for any disease. Use of herbal medicines dates back to 5000 years. An herbal drug has grown exponentially in recent years all across the world. India is considered as the birthplace for Ayurveda, Yoga, Unani, Siddha, Homeopathy and Naturopathy. Because of the belief that”everything can be a drug”, physicians started collection of herbs and popularized it. It has many pharmacological effects and its constituents are extensively used in many clinical applications. This review aimed to explore the constituents present in Citrus limetta and their medicinal uses in different diseases which provide approval for further pharmacological and clinical investigations. This review gives a bird’s eye view mainly on the biological activity its preventive medicinal uses and applications on inflammation, bacterial, viral, diabetes, hyperlipidemia, anxiety, Alzheimer, urinary disorders and for improvement of immune systems. According to the World Health Organization, 75% of the world population use herbal therapies as their primary treatment. It is more popular in rural areas of developing countries. The reason for attaining widespread acceptability includes antimalarial, anti-diabetic, antioxidant, neotropic, lipid lowering activity and minimal side effects with greater efficacy. It is a rich source of Vitamin C and has phytoconstituents like flavonoids, carotenoids, and terpenes. Among them D- limonene is the most abundant constituent. Objective of the review is to maximize the review of Citrus limetta focusing the effect over different ailments and isolation of different constituents from this plant for different sets of diseases.
Keywords: Mosambi, Citrus Limetta, Flavonoids, Limonene, Hyperlipidemia, Antioxidant
