Figure 2 - uploaded by Eduardo Marín-Hernández
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A. Panoramic view of the dilated follicles in the area of the bulb and isthmus. Hematoxylin-eosin stain (4X). B. Keratin plug with abundant Malassezia yeasts. Hematoxylin-eosin stain (10 X). C. Detail of the yeasts. Hematoxylin-eosin stain (20X).
Source publication
Background:
Folliculitis due to Malassezia spp. (MF), caused mainly by Malassezia furfur, is clinically characterized by an acneiform eruption expressing follicular papules and pustules, predominantly on the trunk. Diagnosis of MF requires confirmation of the presence of yeasts in the hair follicle. The treatment of choice is topical or oral with...
Contexts in source publication
Context 1
... forearm biopsy, a mycologic study of the face, and the pustular lesion on the neck were performed. Histology showed epidermis with orthokeratosis and irregular moderate acanthosis, identifying dilated follicles, mainly in the bulb and isthmus area, with the presence of a keratin plug and spherical microorganisms compatible with Malassezia yeasts (Figure 2). Mycological examination reported the presence of yeasts, and culture showed the presence of Malassezia. ...
Context 2
... forearm biopsy, a mycologic study of the face, and the pustular lesion on the neck were performed. Histology showed epidermis with orthokeratosis and irregular moderate acanthosis, identifying dilated follicles, mainly in the bulb and isthmus area, with the presence of a keratin plug and spherical microorganisms compatible with Malassezia yeasts (Figure 2). Mycological examination reported the presence of yeasts, and culture showed the presence of Malassezia. ...
Citations
... In the remaining 99 cases (20%), species identification was not possible; however, the genera, Geotrichum [18,30], Malassezia [104][105][106], Rhodotorula [21,46,[107][108][109], Saccharomyces [109], or Trichosporon [21,39,62,79,91,109,110], were identified. ...
... In the remaining 99 cases (20%), species identification was not possible; however, the genus, Geotrichum [18,30], Malassezia [104][105][106], Rhodotorula [21,46,[107][108][109], Saccharomyces [109], or Trichosporon [21,39,62,79,91,109,110], was determined. ...
Systemic infections caused by rare yeasts are increasing given the rise in immunocompromised or seriously ill patients. Even though globally, the clinical significance of these emerging opportunistic yeasts is increasingly being recognized, less is known about the epidemiology of rare yeasts in Latin America. This review collects, analyzes, and contributes demographic and clinical data from 495 cases of infection caused by rare yeasts in the region. Among all cases, 32 species of rare yeasts, distributed in 12 genera, have been reported in 8 Latin American countries, with Trichosporon asahii (49.5%), Rhodotorula mucilaginosa (11.1%), and Saccharomyces cerevisiae (7.8%) the most common species found. Patients were mostly male (58.3%), from neonates to 84 years of age. Statistically, surgery and antibiotic use were associated with higher rates of Trichosporon infections, while central venous catheter, leukemia, and cancer were associated with higher rates of Rhodotorula infections. From all cases, fungemia was the predominant diagnosis (50.3%). Patients were mostly treated with amphotericin B (58.7%). Crude mortality was 40.8%, with a higher risk of death from fungemia and T. asahii infections. Culture was the main diagnostic methodology. Antifungal resistance to one or more drugs was reported in various species of rare yeasts.
