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(A) MARPE expander with hybrid anchorage inserted into the oral cavity; (B) an accentuated vascular pattern was observed at the six-week check-up stage.
Source publication
The most common inflammatory reactions in the oral mucosa are found at the gingival
level. The treatment of these inflammations requires, first of all, the removal of the causative factor; often, this maneuver is sufficient. The aim of this retrospective study was to evaluate clinical and histopathological changes that occur in terms of gingival an...
Citations
... The oral cavity has several functional structures, including the tongue, salivary glands, cheeks, lips, and palate including teeth, all of which play an important role in physiological processes [35,36]. Histologically, the oral mucosa is a multilayered structure consisting of the epithelium (basement membrane and chorion), and the epithelium presents the stratum basale (basal layer), stratum spinosum (spinous layer), stratum granulosum (granular layer), and stratum corneum [35][36][37][38]: - ...
... These cells have intensely colored voluminous nuclei located in the basal third of the cells. Basal cells exhibit intense metabolism and frequent mitoses that provide flaking turnovers [35][36][37][38]; - ...
... The nuclei of the cells of the spinosum stratum stain less intensely than the nuclei of the cells of the stratum basale, so that the stratum spinosum is well delineated from the stratum basale. The cells in the deep areas of the stratum spinosum show mitosis and together with the basal cells form the germinative zone of the epithelium, and towards the surface, the cells of the stratum spinosum become fla er [35][36][37][38]; - ...
In this study, we focused on innovative approaches to improve drug administration in oral pathology, especially by transmucosal and transdermal pathways. These improvements refer to the type of microneedles used (proposing needles in the saw), to the use of certain enhancers such as essential oils (which, besides the amplifier action, also have intrinsic actions on oral health), to associations of active substances with synergistic action, as well as the use of copolymeric membranes, cemented directly on the tooth. We also propose a review of the principles of release at the level of the oral mucosa and of the main release systems used in oral pathology. Controlled failure systems applicable in oral pathology include the following: fast dissolving films, mucoadhesive tablets, hydrogels, intraoral mucoadhesive films, composite wafers, and smart drugs. The novelty elements brought by this paper refer to the possibilities of optimizing the localized drug delivery system in osteoarthritis of the temporomandibular joint, neuropathic pain, oral cancer, periodontitis, and pericoronitis, as well as in maintaining oral health. We would like to mention the possibility of incorporating natural products into the controlled failure systems used in oral pathology, paying special attention to essential oils.
