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(A) Initial ClinCheck ® , (B) final ClinCheck ® and (C) superimposition of A and B. The ClinCheck ® simulation shows the degrees of correction of the rotations. (E) Initial intra-oral photo on the lower arch, (F) final intra-oral photo on the lower arch and (D) summary of changes of (E) and (F). The correction of the rotations on the ClinCheck ® and on the photos are similar. 

(A) Initial ClinCheck ® , (B) final ClinCheck ® and (C) superimposition of A and B. The ClinCheck ® simulation shows the degrees of correction of the rotations. (E) Initial intra-oral photo on the lower arch, (F) final intra-oral photo on the lower arch and (D) summary of changes of (E) and (F). The correction of the rotations on the ClinCheck ® and on the photos are similar. 

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The present adult patient case report shows the correction of a crossbite malocclusion and severe tooth rotations treated with the Invisalign system. A 27-year-old female with a dental crossbite (24, 34), severe rotations of two lower incisors (more than 40 degrees) and malalignment of the upper and lower arches is described. The Invisalign system...

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... recent years, increasing numbers of adult patients have sought orthodontic treatment 1 and expressed a desire for aesthetic alternatives to conventional fixed appliances. 2 The possibility of using clear overlay appliances to achieve an orthodontic result was introduced in 1946, when Kesling 3 devised the concept of using a series of thermoplastic tooth positioners to progressively move malaligned teeth to impoved positions. In 1997, Align Technology (Santa Clara, CA, USA) adapted and incorporated modern technologies to introduce the Invisalign system which made Kesling’s concept a feasible, efficent and effective orthodontic treatment option. In 2000, Boyd et al. 4 published the first case report on the use of clear aligners and indicated that the primary benefit of the Invisalign appliance was the superior aesthetics during treatment, compared with metal braces. The Invisalign system 5,6 is based on a clear sequential appliance (aligners) made from a translucent thermoplastic material, which is worn for at least 20 hours per day. According to current protocols, the appliances are replaced on a bi-weekly regimen which incorporates a progressive alignment of up to 0.25 mm translation or up to 2 degrees of rotation per tooth per aligner. Malocclusions treated with the Invisalign system initially involved only mild crowding of 3-6 millimetres. 7 Recent data has expanded the use of this appliance to incorporate molar distalisation, 8 extraction cases, 9 the treatment of open bites, 10 crossbites, 7 deep bites, 11 Class II 8 and Class III corrections 12 and orthodontic-periodontic problems. 13 Rotation is an orthodontic movement reported to be difficult to achieve and control with the Invisalign system. Previous studies 14,15 have demonstrated that aligners were not able to control the rotation of canines requiring rotational movements greater than 15 degrees, which underlined the fact that the effectiveness of canine derotation was questionable. Recently, many new biomechanical features have been promoted by Align Technology to improve the predictability of aligner treatment. In particular, the G3 and G4 platforms introduced a collection of newly engineered attachments to improve control of desired tooth movements, including dental rotation and root tipping. The present case report describes an adult patient in whom the correction of a crossbite malocclusion with severe tooth rotations was successfully achieved with the Invisalign system. A 27-year-old female patient with a dental crossbite (24, 34), severe rotations of two lower incisors (more than 40 ° ) and malalignment of the upper and lower arches presented for orthodontic treatment (Figure 1). Informed consent was obtained from the patient who underwent examination and record taking. This involved clinical, orthodontic and temporomandibular disorder (TMD) evaluations, 16 a radiographic assessment (panoramic), lateral cephalometry (Figure 2), stone casts, intra-oral (Figure 1) and extra-oral photos, and upper and lower arch impressions to generate a ClinCheck ® assessment. The clinical examination revealed a molar and canine Class I relationship, an overjet of 1 mm, an overbite of 2.5 mm, a crossbite between teeth 24 and 34, upper and lower crowding, and severe rotations of lower incisors (32 rotated 45 ° and 42 rotated 44 ° ). The assessment of the temporomandibular joints 17 revealed no signs and/or symptoms of TMD. Cephalometric analysis showed a skeletal Class I-III relationship according to Steiner 17,18 with an ANB angle of -1 degree (mean of 2 ° ± 2 ° ), a hypodivergent craniofacial form indicated by a SN-GoGn angle of 27 degrees (mean of 32 ° ± 4 ° ), an interincisal angle of 145 degrees (mean of 135 ± 5 ), a counterclockwise growth rotation according to Siriwat and Jarabak, 19 with a PostHt/AntHt ratio of 72% (mean of 60-64%) and a counterclockwise growth rotation according to Bjork 21 of 387 degrees (mean of 396 ° ± 6 ° ). Invisalign treatment was planned to correct the dental crossbite, the severe rotations of 32 and 42 and the upper and lower malalignment. The final ClinCheck ® (version 2.9, Align Technology Inc., Santa Clara, CA, USA) provided 17 aligners for the upper arch and 23 aligners for the lower arch (Figures 3 and 4). The duration of therapy was assessed to require approximately 12 months. Each aligner was to be worn for two weeks. No inter-proximal reduction (IPR) was indicated for the correction of the crowding. Retention attachments were planned on several upper teeth (13, 14, 23, 24, 26, 27) and on several lower teeth (32, 33, 34, 36, 42, 43, 44, 45). Treatment progress was checked every 4 weeks (2 aligners every month) using the ClinCheck ® analysis to evaluate changes, patient compliance and bonded attachment stability. A new aligner was inserted at each appointment. The precise relationship and connection between the attachments, the aligner and the teeth, provided an indication of the positive progress of treatment. As compliance is critical in all orthodontic therapy, the patient was instructed to wear the aligners full time, except for eating and tooth brushing. The aligners were worn for a minimum of 20 hours per day. A patient with a dental crossbite, severe rotations of lower incisors and malalignment of the upper and lower arches was treated with the Invisalign appliance. Patient compliance was high throughout treatment and excellent oral hygiene was maintained. The molar and canine Class I relationships were maintained, as well as the overjet. The overbite improved (2.5 mm pretreatment, 1 mm post-treatment); the dental crossbite, the crowding (Figure 5) and the severe tooth rotations (with a mean of 2 ° of correction per aligner) were corrected (Figure 6). No obvious root resorption was radiographically evident at the end of therapy (Figure 7). A lower fixed retainer was bonded from the right first premolar to left first premolar to maintain lower incisor alignment. Retention in the upper arch was provided by the last aligner used as a nocturnal removable retainer. In 2003, Joffe 20 defined the criteria for selecting Invisalign patients and emphasised that caution should be taken in specific malocclusions involving severe tooth rotations (more than 20 ° ). In the presented case, a correction of 45 degrees and 44 degrees for teeth 32 and 42 respectively, was achieved with 23 lower aligners, using accepted treatment protocols. The rotated incisors were derotated approximately 2 degrees per aligner and the final result was achieved in 12 months. This result may be due to the recent significant improvement in Invisalign technology which has allowed the treatment of more difficult malocclusions over a shorter time. The introduction of the G3 and G4 platforms with new smart force features has also potentially allowed more predictable tooth movement. The Invisalign system can be a useful therapeutic tool to correct a dental malocclusion involving severe rotations. The presented case confirmed that: 1. The correction of a crossbite in an adult patient is possible with clear aligners. 2. Severe tooth rotations of lower incisors (up to 45 ° ) can be corrected with clear aligners. The logistical support of Equipe Dentale Srl was greatly ...

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... Clear aligners emerge as the times require. Clear aligners have currently been used for more complex orthodontic tooth movements, including tooth rotation, molar distalization, and dental expansion with the advancement of attachments and materials, and their application scope has been extended from non-extraction to extraction cases [4,[16][17][18]. Therefore, according to the requirement of this patient, we chose clear aligners to overcome the aesthetic defects in the orthodontic treatment process. ...
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... As clear aligner technology has made dramatic progress in recent years, its use has become more practical even in mild-to-severe malocclusion cases. 1,2 According to Hennessy and Al-Awadhi, 3 clear aligner treatment (CAT) can achieve expansion, constriction, intrusion, extrusion, tipping, buccolingual tipping, and rotation of the anterior dentition through tooth movement. 3 Unfortunately, the overall accuracy of CAT's tooth movement is reported to be only 41%. ...
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... 6 Numerous successful cases supporting that clear aligner therapy can treat almost any orthodontic condition ranging from mild to severe malocclusions have been reported. 6,7 White spot lesions (WSLs) are defined as occasional white or ashy grey lesions of a small surface area limited to tooth enamel. 8 The difference in the refractive index between healthy enamel and demineralised area results in a lesion of milky-white opaque appearance that is readily distinguishable from the surrounding healthy enamel. ...
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... With the advancement of attachments and materials, CAT is currently used for more complex orthodontic tooth movements, including molar distalization, dental expansion, and tooth rotations. [3][4][5] Alveolar bone defects are often manifested in adults before the initiation of OT. 6 Palomo et al 7 have defined alveolar bone fenestrations (ABFs) as areas in which the tooth root is denuded of bone, and the root surface is covered only by periosteum and gingiva, whereas denuded areas involving the alveolar margin have been defined as alveolar bone dehiscences (ABDs). 7,8 The prevalence of ABDs has been reported to vary between 7%-89%, [9][10][11][12] whereas the prevalence of ABFs ranges between 5%-61%. ...
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... With development of material and computer design of tooth movement, the indication of clear aligners has been greatly enlarged. Many researchers reported successful cases to prove that the clear aligners today have been able to treat almost everything from mild to severe malocclusions [2,3]. Fixed braces have been the conventional and effective orthodontic appliance for over a hundred years. ...
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... Severe canine rotation more than 15°(clinically discernable amount of malrotation) is an orthodontic movement reported to be difficult to achieve and control with the Invisalign system [10]. When rotations are greater than 15°, the accuracy of the canine is significantly reduced [11]. ...
... Previous studies have reported that significant rotations of teeth particularly in the mandibular canines have not been achieved satisfactorily using the Invisalign system. [12] In this regard Gianluigi and Tommaso who carried out a treatment with Invisalign found that the rotation of mandibular canines only was achieved one third of the expected and the accuracy of canine rotation (more than 20 degrees) [10] was significantly lower than the rotation of the other teeth [9,13]. ...
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Introduction: The Invisalign system has been used in the orthodontic treatment of numerous types of malocclusions. However some clinicians have reported difficulty incorrecting rotations particularly in canines and premolars using the Invisalign appliance system. This case report describes the orthodontic treatment of an adult patient with severe canine rotation (more than 45°) and crowding on upper and lower tooth.Methods: The clinical examination included extra-oral and intra-oral photographs, panoramic radiographic, lateral cephalometric, stone casts, and upper and lower arch analysis obtained from ClinCheck 3.0.The treatment planning was resolved the crowding in both upper and lower arches and the severe rotation of 33 tooth (46°) using Invisalign system as well as the canine and molar relationship, dental verticalization, adequate over jet, overbite and dental midline using the same system. The duration of the treatment was approximately eight months.Results: In Post-treatment extra oralphotographs, no significant changes were observed at the end of the treatment. Intraoral photographs showed an important and notable improved aesthetics. The canine relationship improved slightly and molar Class Irelationship was maintained. An increase in transverse diameter was observed at the level of first premolars, second premolars and first molars. The overbite was improved. The crowding and the severe canine rotation were corrected. No obvious root resorption was radiographically evident and slight cephalometric changes.Conclusion: The treatment with the Invisalign system resolved the complaint of our patient so this system could be considered as an option that offered good results in the treatment of upper and lower crowding of arches involving severe canine rotation.