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Source publication
As the body’s largest organ, the skin has important roles in barrier function, immune response, prevention of water loss and excretion of waste. Patients with extensive and severe skin lesions would die due to insufficient graftable skin. Commonly used treatments include autologous skin grafts, allogeneic/allogeneic skin grafts, cytoactive factors,...
Context in source publication
Context 1
... skin is the first barrier that protects the body and must be repaired promptly when it is damaged to form a wound. Repairing damaged skin is an extremely complex and dynamic process divided into a hemostatic phase, an inflammatory response phase, a cell proliferation phase, and a skin remodeling phase [5] (Figure 1). The hemostatic phase usually occurs immediately after the appearance of the wound and is dominated by platelets, which undergo an aggregation reaction. ...
Citations
The development of tracheal tissue engineering has seen a rapid growth in recent years. The purpose of this study was to investigate the global status, trends, and hotspots of tracheal tissue engineering research based on bibliometrics and visualization analysis. Publications related to tracheal tissue engineering were retrieved and included in the Web of Science Core Collection. VOSviewer and CiteSpace were used to generate knowledge maps. 655 publications were identified, and the quantity of the annual publications worldwide was on the increase. International collaboration is a widespread reality. The United States led the world in the field of trachea tissue engineering, while University College London was the institution with the greatest contribution. In addition, Biomaterials had a great influence in this field, attracting the largest number of papers. Moreover, the topics of TTE research largely concentrated on the biomechanical scaffold preparation, the vascularization and epithelialization of scaffold, the tracheal cartilage regeneration, and the tissue-engineered tracheal transplantation. And the research on the application of decellularization and 3D printing for the construction of a tissue-engineered trachea was likely to receive more widespread attention in the future.
