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A, B. Photomicrograph (Hematoxylin & Eosin staining, ×100 & × 400) of the left 7th intercostal mass specimen shows tumor cell nests dissecting the fascicles of the skeletal muscle and surrounding soft tissue with some tumor cells located in the lymphovascular spaces. The diagnosis is metastatic ductal carcinoma from the breast.

A, B. Photomicrograph (Hematoxylin & Eosin staining, ×100 & × 400) of the left 7th intercostal mass specimen shows tumor cell nests dissecting the fascicles of the skeletal muscle and surrounding soft tissue with some tumor cells located in the lymphovascular spaces. The diagnosis is metastatic ductal carcinoma from the breast.

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Breast cancer can metastasize to any organ; however, distant metastases are unusual at the time of diagnosis. Furthermore metastasis to skeletal muscle is an uncommon manifestation of malignancy. We report a case of a 45-year-old woman diagnosed with cancer of the left breast with metastases to the ipsilateral intercostal muscle. To the best of our...

Context in source publication

Context 1
... of metastatic ductal carcinoma of the breast. A partial mastectomy for left breast cancer was per- formed and the 2.8-cm tumor was histologically diag- nosed as an invasive ductal carcinoma. The left inter- costal mass was excised en bloc and the pathology re- vealed metastatic breast cancer with all margins of re- section free of carcinoma cells (Fig. ...

Citations

... In the vast majority of situations, SMM remain asymptomatic (as in our case) and only in a few cases may present as local swelling, pain or muscle impairment [2]. The imaging findings may vary from round/oval lesion with homogeneous enhancement or abscess-like lesion to diffuse infiltrating aspect with inhomogeneous enhancement, multiple intramuscular calcifications or even intramuscular bleeding [7] and differential diagnosis is required [8,9]. ...
... To the best of our knowledge, in the literature there are about 39 cases of SMM from breast cancer, but none of them in the pectoralis muscle. Some of these cases have been reviewed from the literature or have come from retrospective studies [2,7,[10][11][12] while ten of them have been published as individual case reports [8,11,[13][14][15][16][17][18][19]. ...
Article
Metastases to the skeletal muscle from breast cancer represent an unusual and rare condition. We present the case of a 27-year-old female with left breast cancer (IDC NST G3) who underwent neoadjuvant chemotherapy followed by conservative surgery (sectorectomy and lymphadenectomy) and radiation therapy. Two months after the end of radiotherapy she presented with a 2 mm skin lesion and she was referred for a screening ultrasound. The screening automated breast ultrasound (ABUS) revealed local recurrence and pectoralis metastases, lesions evaluated also by magnetic resonance imaging. The diagnosis was confirmed by the ultrasound-guided biopsy