FIGURE 1 - uploaded by Irineu Gregnanin Pedron
Content may be subject to copyright.
A, Appearance on extraoral view with broad forehead, hypertelorism, broad nasal bridge, beaked nose, and unusual grimace. B, Keloid scar could be noted in the left side of the mandible. C, Intraoral features characterizing malocclusion with a highly arched and narrow palate and wide alveolar ridges. Utumi et al. Myositis Ossificans Traumatica. J Oral Maxillofac Surg 2010.
Contexts in source publication
Context 1
... parents had no history of consanguinity. Extraoral examinations showed that the patient had a distinctive facial appearance with a broad forehead, hypertelorism, broad nasal bridge, beaked nose, and unusual grimace ( Fig 1A). The patient was referred by a geneticist who diagnosed RTS. ...
Context 2
... patient was referred by a geneticist who diagnosed RTS. An asymptomatic enlargement with keloid scar could be noted in the left side of the mandible (Fig 1B). Other manifestations of the syndrome such as broad thumbs, large and broad toes, short stature, and craniofacial anomalies could be noted. ...
Similar publications
Rubinstein-Taypi Syndrome associated with Breast Cancer
No abstract is available for this article.
Citations
... A few previous consistent observations were not confirmed in our cohort: hypohidrosis, hypothyroidism, hypoglycaemia, and anaesthesia complications [4]. Also, previous individual reports of cervical spine anomalies [10], myositis ossificans traumatica [11], and chronic renal failure of unknown cause [12] were not confirmed in our cohort. ...
The existing knowledge about morbidity in adults with Rubinstein-Taybi syndrome (RTS) is limited and detailed data on their natural history and response to management are needed for optimal care in later life. We formed an international, multidisciplinary working group that developed an accessible questionnaire including key issues about adults with RTS and disseminated this to all known RTS support groups via social media. We report the observations from a cohort of 87 adult individuals of whom 43 had a molecularly confirmed diagnosis. The adult natural history of RTS is defined by prevalent behavioural/psychiatric problems (83%), gastrointestinal problems (73%) that are represented mainly by constipation; and sleep problems (62%) that manifest in a consistent pattern of sleep apnoea, difficulty staying asleep and an increased need for sleep. Furthermore, over than half of the RTS individuals (65%) had skin and adnexa-related problems. Half of the individuals receive multidisciplinary follow-up and required surgery at least once, and most frequently more than once, during adulthood. Our data confirm that adults with RTS enjoy both social and occupational possibilities, show a variegated experience of everyday life but experience a significant morbidity and ongoing medical issues which do not appear to be as coordinated and multidisciplinary managed as in paediatric patients. We highlight the need for optimal care in a multidisciplinary setting including the pivotal role of specialists for adult care.
... The first report found about this condition was reported by Ivy and Eby [5, 9] in 1924. TMO is caused by a major trauma episode or multiple less traumatic events [5, 8, 10]. TMO is widely reported in the orthopedic literature [1, 7, 10, 11]. ...
... TMO is caused by a major trauma episode or multiple less traumatic events [5, 8, 10]. TMO is widely reported in the orthopedic literature [1, 7, 10, 11]. The quadriceps femoris and brachialis anticus are the most affected muscles, particularly in young ath- letes [2, 5, 8, 10,[12][13][14][15]. ...
... TMO is widely reported in the orthopedic literature [1, 7, 10, 11]. The quadriceps femoris and brachialis anticus are the most affected muscles, particularly in young ath- letes [2, 5, 8, 10,[12][13][14][15]. In the facial region, it frequently occurs in the third decade of life and the most affected muscle is the masseter [2–8, 11, 14]. The temporalis muscle seems to be less affected than the masseter and medial pterygoid muscles. ...
Traumatic myositis ossificans (TMO) is a rare ossifying disease that occurs in the muscle or soft tissues. A case of TMO isolated in the temporalis muscle is reported. In the case described, calcification in the temporalis muscle was confirmed after computed tomography. Surgery, physiotherapy, and histopathological analysis were performed. One year after treatment, further ossification was present but without interference in function. The most accepted treatment for TMO in the maxillofacial region is excision followed by physiotherapy. The high rate of non-recurrence may be concealed due to the short follow-up period. TMO is a lesion that may frequently recur and long-term follow-up must be provided.
Introduction
Circumscribed or pseudomalignant myositis ossificans (MO) is a rare and benign condition characterized by heterotopic bone formation in soft tissues. The clinical presentation of MO, imaging investigations, histological findings, and treatment strategies are unclear, especially in the pediatric population.
Materials and methods
A literature search was conducted in PubMed, Scopus, and Google Scholar electronic databases to identify original articles and reviews in English or French of traumatic and non-traumatic MO. Studies were selected by 2 independent reviewers following the PRISMA recommendation and descriptive data were extracted. We harvest in each case the sex, age at diagnosis, location, presence of initial trauma, pre-emptive diagnosis, modalities of imagery used, realized biopsy, treatment performed, and type of follow-up.
Results
Sixty pediatric cases of MO were identified between 2002 and 2023. Twenty-three patients (38.3%) were diagnosed with idiopathic/pseudomalignant and 37 patients (61.7%) with circumscribed. The mean age at diagnosis was 9.5 years (range 0.2–17 years), with a male-to-female ratio of 1:1. The initial pre-emptive diagnosis was neoplasia in 13 patients (21.7%). The biopsy was percutaneous in 9 patients (15%) and incisional in 7 patients (11.7%). Histological analysis was achieved in 35 cases (57%). Surgical excision was the first line treatment in 46.7% of patients, and non-surgical in the remaining patients. The follow-up strategy was clinical in 16 patients (26.7%) or based on imaging investigation in 23 patients (38.3%).
Discussion
Although MO in children is described as a rare pathology, identifying the benignity of the condition is essential to avoid unnecessary invasive treatment and to avoid delaying the treatment of a potentially life-threatening entity. It seems that there is no consensus established concerning the proper imaging for diagnosis. Clinicians should acknowledge that the absence of a triggering trauma tends to direct the investigation and the management toward a surgical attitude. Conservative management is key, however, surgical excision can be proposed on matured lesions on a case-by-case basis. The absence of recurrence is not excluded. Therefore, a close clinical follow-up is suggested for all cases. The true benefit of a radiological is questioned in a question known to be self-resolving.
Introduction:
Traumatic myositis ossificans is rare pathology affecting muscles/soft tissue. Its involvement in temporalis muscle is rarely reported in literature. The aetiopathogenesis is unknown, the diagnosis is based on clinco-radiological findings. Surgical management and follow-up are paramount.
Materials and methods:
A database search was done using Science Direct and PubMed search engines along with other published and unpublished literature. The final publications were tabulated using a custom made Performa. The available publications were subjected to appropriate statistical analysis. The data were recorded on excel spreadsheet (Microsoft Inc), and review was made using Review Manager (Rev Man) software for meta-analysis.
Results:
A total of 21 articles were considered for systemic review and meta-analysis. Forest plotting for demographics included the gender predilection/age of involvement. The data segregation was done with "temporalis involved" group and "other than temporalis involved" group. The study was free of homogeneity ( τ 2 = 0.26 I 2 = 5%) for gender and age. The overall analysis revealed that Temporalis muscle although rare to be affected shows greater propensity for involvement. This is supported by a lesser degree of heterogeneity ( τ 2 = 0.000) with a I 2 value of (The test showed a higher degree of significance for overall effect of muscle involvement (Z = 2.33, p = 0.02) (< 25%). The test showed a higher degree of significance for overall effect of muscle involvement (Z = 2.33, p = 0.02) (< α = 0.05).Case reports.Two male cases with similar age predilection, reported after sustaining trauma. Both the cases presented with limited mouth opening and ultrasound was done for the first time to arrive at clinic-radiological diagnosis. The management was conservative with temporalis myotomy and coronidectomy.
Conclusion:
Traumatic myositis ossificans presents as a rare disorder that poses a dilemma to the treating surgeon. The present article makes an attempt to critically analyse the pathology that is scantly reported in the literature.
