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The potential teratogenic effects of psychotropic medication use during pregnancy have been scrutinized ever since thalidomide contributed to phocomelia in the 1950's. Up to 35% of the half a million women becoming pregnant each day take psychotropic medication(s). Teratogens alter normal intrauterine fetal growth, anatomic structures, functioning...
Contexts in source publication
Context 1
... Her past medical history includes bipolar disorder type 1, GERD, asthma, seasonal allergies, and a congenital seizure disorder. There is no history of familial congenital anomalies. A transvaginal ultrasound performed at 13 weeks gestation detected the plantar surface of the fetal foot in the same sagittal plane as both lower extremity bones (see Fig. 5). Fetal karyotyping showed a 46 XY chromosome. A 1-month old infant presents to the pediatric cardiologist office for follow-up evaluation of the echocardiogram finding shown in Figure 6. The past medical history reveals that the infant was born to a 27-year-old (G3P1011) female at 38 weeks gestation. The murmur noted at birth prompted ...
Context 2
... the forefoot swung medially (adduction at talonavicular joint) and the sole facing inward (inversion at the subtalar joint). This occurs in both feet in up to 30 to 50% of cases. Ultrasound imaging, as early as 12 to 13 weeks of gestation, can detect the plantar surface of the fetal foot in the same sagittal plane as both lower extremity bones (Fig. 5). 49 When clubfoot is suspected, the sonographer should perform a complete anatomic survey, fetal echocardiogram and evaluate the intrauterine environment specifically looking for fetal compression or crowding by fibroids, amniotic bands, or synechiae. Some obstetricians recommend karyotyping via amniocentesis if an at-risk patient is ...
Citations
... 20 In the following 2 years (2013-2014), six faculties supervised seven students and three residents in writing seven educational articles for the Donald School Journal of Ultrasound in Obstetrics and Gynecology. [21][22][23][24][25][26][27] Simultaneously, in 2011 and 2012, the PLFSOM team edited an atlas and three educational DVDs which were designed and recorded at our Center for Advanced Teaching and Assessment in Clinical Simulation (ATACS). 28 The learning objectives are precisely identified, and a list of resources, articles, and other references is clearly presented. ...
... [12][13][14] Approximately, half a million women become pregnant each day, and up to 35% of them use a psychotropic medication at least once before delivery. [15] 15-20% of pregnant women suffer from mental illness, of which 86% remained untreated, and psychopharmacoteratophobia is one reason for the deprivation from treatment. [16][17][18][19] Most of the published reports are case reports, case series, prospective or comparative cohort studies, case-control studies, prescription database studies, and national birth registries done in Western countries. ...
“Psychopharmacoteratophobia is the fear or avoidance of prescribing psychotropic medicine to a pregnant woman on a given indication in anticipation of fetal malformation.” It is rooted in the tragedy associated with thalidomide use and is increasing due to the inability to predict accurately, strict legal provision of consumer
protection, ethical and legal issues involved, and pitfalls in the available evidence of teratogenicity. In the Indian setting, the physicians face more challenges as the majority of the patients may ask them to decide, what is the best for their health. Most guidelines emphasize more on what not to do than what to do, and the locus of decision is left to the doctor and the patient. In this review, we have focused on relevant issues related to
psychopharmacoteraophobia that may be helpful to understand this phenomenon and help to address the deprivation of a mentally ill woman from the required treatment.
... [12][13][14] Approximately, half a million women become pregnant each day, and up to 35% of them use a psychotropic medication at least once before delivery. [15] 15-20% of pregnant women suffer from mental illness, of which 86% remained untreated, and psychopharmacoteratophobia is one reason for the deprivation from treatment. [16][17][18][19] Most of the published reports are case reports, case series, prospective or comparative cohort studies, case-control studies, prescription database studies, and national birth registries done in Western countries. ...
“Psychopharmacoteratophobia is the fear or avoidance of prescribing psychotropic
medicine to a pregnant woman on a given indication in anticipation of fetal
malformation.” It is rooted in the tragedy associated with thalidomide use and is
increasing due to the inability to predict accurately, strict legal provision of consumer
protection, ethical and legal issues involved, and pitfalls in the available evidence of
teratogenicity. In the Indian setting, the physicians face more challenges as the majority
of the patients may ask them to decide, what is the best for their health. Most guidelines
emphasize more on what not to do than what to do, and the locus of decision is left to
the doctor and the patient. In this review, we have focused on relevant issues related to
psychopharmacoteraophobia that may be helpful to understand this phenomenon and
help to address the deprivation of a mentally ill woman from the required treatment.
