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The Omega-3 Fatty Acid Deficiency Syndrome: Opportunities for Disease Prevention; Chapter 13. Omega-3 Fatty Acids – Opportunity for Cancer Prevention?
ResearchGate has not been able to resolve any citations for this publication.
A main function of adipose tissue is to store surplus energy however providing mechanical support and cushioning vital organs for protection from injury and extremes of weather conditions are equally important functions of body fat. However, excess body fat (overweight/obesity), particularly in the abdominal region has been associated with adverse health effects including diabetes mellitus and cardiovascular disease. In recent years, adipose tissue has been recognized as an endocrine gland actively secreting hormones, cytokines and other regulatory substances that play important role in energy balance, glucose metabolism, regulation of blood pressure and the immune system. Development of obesity is also characterized by a chronic low grade inflammation in the adipose tissue. Epidemiological and interventional studies suggest that bioactive food components such as LCn-3PUFA (eicosapentaenoic acid, EPA and docosahexeanoic acid, DHA) can modulate the inflammatory process and assist in weight loss and/or slow-down weight gain. Expression of genes involved in fat synthesis and oxidation in adipose tissue, coupled with increase in satiety hormones and enhanced blood flow to muscles, appear to mediate weight loss following LCn-3PUFA supplementation. Recent research has also raised the possibility that LCn-3PUFA supplementation may have differential effects on weight loss and body composition in males versus female subjects. Precise mechanisms by which LCn-3PUFA hasten weight loss and/or suppress weight gain merit further investigation, as does the role of EPA versus DHA in weight management.
Central Nervous System Disorders Chapter 14 The Putative Role of Long-Chain Polyunsaturated Fatty Acids for Prevention and Treatment of Retinal Diseases
- Iii Section
Section III. Central Nervous System Disorders
Chapter 14. The Putative Role of Long-Chain Polyunsaturated Fatty Acids for
Prevention and Treatment of Retinal Diseases
(John Paul SanGiovanni, Clinical Trials Branch, National Eye Institute, National
Institutes of Health, NIH Clinical Center, Bethesda, MD, USA)
Pathological and Therapeutic Implications of Omega-3 Fatty Acids in Schizophrenia
- Jeffrey K Yao
- Ravinder Reddy
- Ruth Condray
- Tao Long
- Gretchen Haas
Chapter 17. Pathological and Therapeutic Implications of Omega-3 Fatty Acids in
Schizophrenia
(Jeffrey K. Yao, Ravinder Reddy, Ruth Condray, Tao Long and Gretchen Haas, VA
Pittsburgh Healthcare System, Pittsburgh, PA, USA and others)
Approaches and Standards Chapter 19 Standardizing Methods for Assessing Omega-3 Fatty Acid Biostatus
- Iv Section
Section IV. Approaches and Standards
Chapter 19. Standardizing Methods for Assessing Omega-3 Fatty Acid Biostatus
(William S. Harris, Clemens von Schacky and Yongsoon Park, OmegaQuant, LLC,
and Sanford School of Medicine, University of South Dakota, Sioux Falls, SD, USA