Carob (Ceratonia siliqua L.) is a tree species native to the Mediterranean region and belongs to the Fabaceae family. Te tree is well-known for its sweet and nutritious fruits, which have been used for long time as a nutritious food. In addition to the edible fruits, the carob tree also produces seeds that are highly prized for their ability to produce carob gum (locust bean gum). Te carob seed consists of three main components: the shell, the endosperm, and the embryo. Te shell is the outermost layer of the seed, followed by the endosperm, which is the largest part of the seed and contains high levels of carbohydrates and proteins. Te embryo is the smallest part of the seed and is rich on bioactive compounds. Carob seed constituents have attracted considerable attention due to their exceptional nutritional and therapeutic properties in various industries, including food, medicine, pharmaceuticals, cosmetics, and textiles. Te high content of bioactive compounds in carob seeds, such as polyphenols, tannins, and favonoids, is believed to be responsible for their antioxidant and anti-infammatory properties. Te use of carob seed constituents in the food industry is mainly due to their ability to act as thickeners and stabilizers in various foods. Tey are used as a substitute for other thickening agents such as guar gum and carrageenan, due to their superior properties. In the pharmaceutical industry, carob seeds have been found to have antidiabetic, antihyperlipidemic, and anticancer properties, among others. Te cosmetics industry is also interested in the ingredients of carob seed, as they can improve hydration and elasticity of the skin. Tey are also used as a natural alternative to synthetic thickeners in cosmetic formulations. Te textile industry has also recognized the potential of carob seed constituents, as they can be used as a natural dye and as a sizing agent to improve the strength and durability of textiles. In summary, carob seed constituents ofer a wide range of applications in various industries, owing to their high content of bioactive compounds, excellent nutritional and therapeutic profle, and ability to act as thickeners, stabilizers, and antioxidants. Tis review has highlighted the latest fndings on the chemical composition, applications, and health benefts of carob seed constituents.